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GLG News by Lung Cancer Oncologists (US)

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March 7, 2008
American Cancer Society is promoting money in CaCa analysis?
Analysis of: Two Tests Added to Recommended List to Prevent or Detect Colorectal Cancer | www.nytimes.com
Author: GLG Expert Contributor
Virtual Colonoscopy and stool analysis for DNA alterations for colon cancer, are being recommended for screening.
March 6, 2008
Heparin: Unfractionated Heparin, more expensive, less effective and dangerous compared to low molecular weight varieties
Analysis of: Acute Pulmonary Embolism | content.nejm.org
Author: GLG Expert Contributor
     With recent developments in preparation of unfractionated heparins (http://www.nytimes.com/2008/03/06/health/06heparin.html?_r=1&ref=health&oref=slogin) not only are the LMWH varieties more effective as well as cheaper when all of the co factors are included, they...
March 5, 2008
Cholesterol lowering: to advertise or not???
Analysis of: Drug Pitchmen: Actor, Doctor or Pfizer’s Option | www.nytimes.com
Author: GLG Expert Contributor
"Celebrity" advertisements of percription drugs are disingenuous?
March 3, 2008
Teva Camptosar: significance?
Analysis of: Teva Announces Approval Of Generic Camptosar(R) | www.pipelinereview.com
Author: GLG Expert Contributor
Camptosar is being made in Israel I would imagine, and the price differential compared to Pfizer's brand name drug is????
February 29, 2008
Anesthesia in Colonoscopies: I have an idea for a clinical trial!
Analysis of: Aetna to Delay Reduced Colonoscopy Coverage | online.wsj.com
Author: GLG Expert Contributor
The original plan was to not provide for anesthesia support during the uncomfortable, to say the least, colonoscopys as well as upper endoscopy.
February 28, 2008
Novartis's Everolimus: On it's way to being a competitor for Wyeth's Torisel.
Analysis of: Novartis Late-State Cancer Trial Is Stopped Early After Meeting Goal | online.wsj.com
Author: GLG Expert Contributor
It shares a common mechanism of action with Wyeth's Torisel (mTOR inhibition) and will at least share the market for recurrence after a TK inhibitor fails.
February 27, 2008
Procrit, Aranesp, Epogen: OMG (O my God) now JAMA piles on.
Analysis of: Higher Risks Found for Anemia Drugs | online.wsj.com
Author: GLG Expert Contributor
Meta analysis of multiple papers shows an increased risk of dealth in cancer patients receiving Epo products.
February 26, 2008
CEP-18770 (Cephalon & Cell Therapeutics Europe) an oral proteosome inhibitor: Millenium beware
Analysis of: CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib | bloodjournal.hematologylibrary.org
Author: GLG Expert Contributor
IF this agent works it is ORAL and will certainly be more acceptable to patients than the IV Velcade.
February 26, 2008
Gene Directed Therapy: I told you so!! Roche Holding on the right track!
Analysis of: Study: More Complexity In Tailoring Cancer Drugs | online.wsj.com
Author: GLG Expert Contributor
Roche Holding may well be leading the way to make gene analysis more cost effective and individualize cancer care by targeting the mutations!!
February 25, 2008
Gardasil: Cervical Cancer Vaccine for Boys?? Can you say disingenuous?
Analysis of: Vaccinating Boys for Girls’ Sake? | www.nytimes.com
Author: GLG Expert Contributor
Merck intends to market this viral vaccine to "protect" women from the risk of cervical carcinoma.

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