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GLG News by Immunologists (US)

December 17, 2008
LABA and the FDA
Analysis of: FDA: Long-Acting Asthma Drugs Increase Asthma Risks (online.wsj.com)
The FDA is considering removing single drug long acting Beta Agonist from the market. They believe they have the potential to cause harm. They are considering removing component therapy drugs that contain long acting Beta agonist like Symbicort and Advair also. This would lead to a major problem for...
Analysis of: Gardasil, Merck's Cervical Cancer Vaccine, Demonstrated Efficacy in Preventing HPV-Related Disease in Males in Phase III Study (www.fiercebiotech.com)
The new HPV vaccine which has been so successful in preventing HPV disease in females has now proven to be successful in preventing genital warts and penile cancer in  males. The quadravalent vaccine which cover 90% of currently circulating human HPV strains, has proven to be approximately 90%...
Analysis of: COPD Medicines: Risky or Safe? (www.webmd.com)
In a recent article it is noted that for users of Ipatropium bromide there was an increase in all death and cardiac death in the group studied.  Theoretically at doses normally used there is not much of a corresponding mechanistic risk.  Therefore at this time additional study must be done...
David Engler, MD, Physician
David Engler, MD, Physician
The Allergy Clinic
Analysis of: Medicare fees to doctors fall Tuesday (news.yahoo.com)
If this isn't fixed, it won't be long before cognitive specialties, like internal medicine and neurology, start capping their practices and not allowing new Medicare patients.    
David Engler, MD, Physician
David Engler, MD, Physician
The Allergy Clinic
Analysis of: Taro Receives Final FDA Approval For RX Cetirizine Hydrochloride Syrup ANDA (www.medicalnewstoday.com)
Here comes a prescription version of generic Zyrtec syrup.  At first glance, we wonder how it will compete with over the counter Zyrtec.  But wait...there may be a market for this drug    
June 23, 2008
EMRS
Analysis of: Most Doctors Aren’t Using Electronic Health Records (www.nytimes.com)
mY 6 PERSON GROUP HAS INSTALLED AN EXPENSIVE EMR ABOUT 6 MONTHS AGO . WHILE IT HAS BENEFITED US IN MANY WAYS (BETTER RECORD KEEPING FOR EXAMPLE) IT HAS BEEN VERY EXPENSVE TO INSTALL AND IMPLEMENT (HAVING TO HIRE A TECH GUY TO HELP US WT SERVER CRASHES , ETC THAT OCCUR WEEKLY).  IN ADDITION THE...
David Engler, MD, Physician
David Engler, MD, Physician
The Allergy Clinic
Analysis of: Investigational Anti-IgE Antibody Promising as Extracorporeal Allergy Therapy (www.medscape.com)
This drug seems much more effective at reducing free-IgE levels than is Xolair.  Overall, Xolair has given many patients a tremendous improvement in their quality of life, but it hasn't fulfilled many of its promises. Frankly, some of Xolair's benefits are disappointing, particularly in the 40...
June 16, 2008
exenatide
Analysis of: After One Year, Type 2 Diabetes Patients Taking Exenatide Once Weekly Sustained Improvements in Glycemic Control and Weight; DURATION-1 Presented at ADA 2008 (newsroom.lilly.com)
Once a week treatment for diabetes with no weight gain.
June 16, 2008
mab12
Analysis of: Investigational Anti-IgE Antibody Promising as Extracorporeal Allergy Therapy (www.medscape.com)
more prescribing habits of a more potent antibody. It also would be preferred for those patients whose IgE levels are too great fro treatment with Xolair.
Analysis of: China Muscles In On The Generics Industry (www.pharmalot.com)
The Chinese government funded many manufacturing plants for biologics about 15 years ago, and many are bankrupt because of noninforced patent laws

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