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March 19, 2007
Vaccine would have a major impact on world health
Analysis of: Novel tuberculosis vaccine shows promising immunogenicity and safety profile | www.pipelinereview.com
Author: GLG Expert Contributor
Article describes a new promising TB vaccine.
February 21, 2007
Autism is Rising: Treatments are Lagging
Analysis of: Are Autism Cases on the Rise in U.S.? | www.nlm.nih.gov
Author: GLG Expert Contributor
Autism is a part of Autistic Spectrum Disorders, which also includes Asperger’s syndrome, childhood disintegrative disorder, and Rett syndrome.  The recent release of CDC statistical data confirmed that prevalence of autism has increased to 1/150 young children, which is higher than previous e...
December 8, 2006
Potential Comeback of Anti-schizophrenia Drug Iloperidone, Or Maybe Not!
Analysis of: Vanda Pharma Schizophrenia Drug Effective | biz.yahoo.com
Author: GLG Expert Contributor
Anti-schizophrenia Drug iloperidone was initially developed as a joint venture between Titan Pharmaceuticals and Novartis.  However, Novartis halted the development of this drug due to its cardiovascular side effects. Vanda Pharmaceuticals (a near spin off from Novartis) picked up iloperidone and...
October 30, 2006
FDA approval for severe Alzheimer's disease
Analysis of: Aricept (donepezil) Wins Indication for Severe Alzheimer's | www.medpagetoday.com
Author: GLG Expert Contributor
It is long waited decision. I have been using donepezil for last 4 to 5 years in moderate to severe Alzheimer's disease with good results. Only, I did not have statistical data.
October 25, 2006
AstraZeneca is Flying High with Seroquel®
Analysis of: FDA Approves AstraZeneca's Seroquel® For Bipolar Depression Treatment | www.medicalnewstoday.com
Author: GLG Expert Contributor
The depressive episode of bipolar disorder is more difficult to treat and appears to limit or slow treatment response, and contributes importantly to disability and mortality. Modern antidepressants have been widely used for treatment of bipolar depression, but they worsen acute mania. Therefore, use...
October 23, 2006
Alzheimer Patients: No More Antipsychotics
Analysis of: Antipsychotics No Better Than Placebo for Alzheimer's Patients | www.nlm.nih.gov
Author: GLG Expert Contributor
Alzheimer patients commonly develop psychosis, anxiety, agitation and aggression. These symptoms affect the quality of life of these patients and their families. Second generation or “newer” antipsychotic drugs are widely used to treat these symptoms, in spite of the absence of clinical evidence to...
October 20, 2006
Antipsychotic Drugs: Old is Gold
Analysis of: Newer Schizophrenia Drugs May Be No Better | www.nlm.nih.gov
Author: GLG Expert Contributor
Second generation or “newer” antipsychotic drugs dominate the global market share with annual sales over $10 billion.  Last year’s huge NIH-funded CATIE study suggested that these fancy drugs are not superior to or more effective than the less expensive first generation or “older” antipsychotic...

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