Analysis of:
Gallstone Risk Seen With Roche Weight Drug Xenical: FDA Staff (www.medscape.com)
Gallstones are a minor clinical problem compared with Roche's Orlistat's oily leakage, perceived by patients as a major deterrent to use.The business risk is to sales of GSK's Alli, to be released later this year.Litigation from recent cholecystectomy patients is, however, a possibility as is class...
Analysis of:
Abbott Announces FDA Approval of a New Coated Niaspan Tablet (pharmalive.com)
*The major problem with Niaspan is being missed: it is not flushing, it is the liver and the muscles*Much of the target audience cannot take extended release niacin...statin takers, for example*Making supplements into drugs requires a better understanding of what consumers want from both
Analysis of:
Dark Chocolate May Lower Risk Of Cardiovascular Disease (www.medicalnewstoday.com)
Dark chocolate has staying power as a functional food and nutraceutical.Peripheral arterial disease, impotence and small vessel disease in diabetes may be improved with better flow mediated dilation, shown here.Sugar could cripple the cocoa, as could cocoa processing.
Analysis of:
Alba Announces Completion of Enrollment and Dosing of Patients in Phase II Clinical Trial of AT-1001 for the Treatment of Celiac Disease (www.pipelinereview.com)
Yes, there are 3m undiagnosed celiacs in the U.S. I wonder if they want to take a compound so they can still eat pasta...which they currently eat.State of the art design, but uncertain why 6m instead of 12m, as absorption problems can continue after 6m.Fascinating possibility that Alba could be right...but...
Analysis of:
The Road to Wellness Is Starting at the Office (online.wsj.com)
Use HR to sell wellness to your employeesExpect to pay for, develop and profit from wellness programs yourself: your insurer has not yet figured it out.Improving employee health is the same as cutting medical costs, without killing morale and sprouting lawsuits.
Analysis of:
Obesity pill may treat diabetes (heartpro.healthcentersonline.com)
* Rimonabant has promising science but certain side effects, especially psychological side effects* Treating diabetes has a certain future, while treating obesity with pharmacologic mechanisms has certain, well-known cautions* Differently than what is stated here, there are 2 other diabetes drugs on...
Analysis of:
Belly Bacteria Linked to Obesity (www.foxnews.com)
1. Infectobesity, or obesity resulting from infection, is reproducible in mice, and implied in people.2. This is most likely not a fad: there is serious money, and serious research, and it is scientifically logical3. If there was one diet that worked, we would all be on it: the cause of weight gain...
Analysis of:
Inhaled Insulin for Diabetes Mellitus (content.nejm.org)
*Weight loss must be taken into account in agent selection*90 percent of type II patients are overweight...not so type I*The epidemic of diabetes is nearly all type II patients, and most do not require insulin, and should not.
Analysis of:
Investor Appetite is What Diet Firm May Really Lose (online.wsj.com)
*Investor and management ownership/recent sales of NTRI, up 2461 percent in 2 years.*Little (needed) detail of actual operations, dietary content*Marketing weight loss as a strategy for long term success
Analysis of:
An Old Cholesterol Remedy Is New Again (www.nytimes.com)
*The major problem with niacin and MK-0524 is being missed*Much of the target audience cannot take niacin*Making supplements into drugs requires a better understanding of what consumers want from both