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GLG News by HemoSense PT/INR Testing Sytem Users

Robert Boorstein, MD, PhD, Director of Pathology
Bellevue Hospital Center
Analysis of: Merck Serono: Study Published In JCO Shows Erbitux Enhances Efficacy In MCRC Patients With KRAS Wild-Type Tumors In 1st-Line Setting (www.medicalnewstoday.com)
This study is one that adds to an increasing body of evidence linking specific molecular testing to treatments with expensive and potentially dangerous antichemotherapeutic agents.
Analysis of: New data show Tekturna HCT® is twice as effective at reducing blood pressure than the diuretic HCT alone (www.novartis.com)
It is well known that the addition of thiazide diuretic to ACEI or ARB treatment adds about 10 mm Hg reduction on top of the 10 mm Hg reduction provided by the ACEI or ARB agent.  It is expected that blocking renin in the renin angiotensin system with Tekturna would provide a similar result.
Joseph Schappert, MD, Medical Director
Icon Central Laboratories, Inc.
Analysis of: Kidney Cancer Drug Linked to Higher Rate of Heart Problems (www.washingtonpost.com)
Diagnostic tools are availible to identify these adverse effects at an early stage in their clinical development. These tools should mitigate the seriousness of these adverse events.
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
February 19, 2008
Avastin In Breast cancer
Analysis of: In Second Trial, Avastin Is Found Effective in Treating Breast Cancer (www.nytimes.com)
New data with low and high dose of Avastin with Taxoter
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
Analysis of: Dendreon Presents Data Correlating the Cumulative Potency of PROVENGE(R) to Overall Survival (www.pipelinereview.com)
esults showed that PROVENGE patients experienced improved survival if they received more cells across the three doses of PROVENGE (higher cumulative TNC count (p=0.019)) or higher cumulative CD54 upregulation values (p=0.009). The effect on survival for TNCs appeared to reflect in part the patients'...
Analysis of: Daiichi Sankyo, Lilly Submit New Drug Application for Investigational Antiplatelet Drug, Prasugrel, with U.S. Food and Drug Administration (www.pipelinereview.com)
TRITON-TIMI 38 study of 13,608 patients with ACS compared prasugrel against clopidogrel, combined with aspirin.  Prasugrel reduced the combined rate of CV death, MI or stroke (12.1% for clopidogrel vs. 9.9% for prasugrel). The benefit came at a cost of increased serious bleeding (1.4%, vs....
Analysis of: Schering releases ENHANCE data today (www.tradingmarkets.com)
Physicians have several possible conclusions that can be taken; These include: - the trial is flawed - the selection of patients with much less CIMT than previous trials such as ASAP and ARBITER flaws the study -  the failure to meet the trial endpoint is only a surrogate and clinical trial data...
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
December 7, 2007
Avastin in breast cancer
Analysis of: F.D.A. Criticizes Avastin Use for Breast Cancer (www.nytimes.com)
“On face value the data look very good,” said Buzdar, who voted with the slim (5-4) majority against the drug. In the study that was the basis of Genentech’s application, Avastin appeared to slow the progress of the disease. advanced breast cancer who had already tried other drugs. He said he’s never...
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
August 29, 2007
CMS
Analysis of: New Medicare Regulations Adopted To Reduce Certain Hospital Infections And Medical Errors (www.medicalnewstoday.com)
CMS is doing right thing. This will aviod pt fall and bedsore during hospitalzation
August 28, 2007
Medical Tourism
Analysis of: American's Gamble for Bargain Surgery Abroad (www.medpagetoday.com)
Medical Tourism is purely linked to lower costs for the same procedure.Most of these relate to 1)Small elective surgeries 2) Non-Urgent Cardiac and Non-Cardiac Procedures and Operations 3)Cosmetic Procedures 4)Dental and Vision corrective procedures 5)Radiologic Procedures(Diagnostic and Ther...

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