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GLG News by Hematologists (US)

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August 29, 2008
Velcade in myeloma 1st line. Am I s?urprised
Analysis of: Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma | content.nejm.org
Author: GLG Expert Contributor
Velcade + classic Melphalan/ Prednisone  (MP) is better than MP alone. No surprise
August 25, 2008
Amgen's long awaited product to treat chronic ITP will be well receive.
Analysis of: Amgen Blood-Disorder Drug Gains Clearance | online.wsj.com
Author: GLG Expert Contributor
Chronic ITP is not all that uncommon and becomes a quality of life issue with chronic steroid use as well as agents that are normaly used in neoplasia and even derivatives of male hormones.
August 21, 2008
Artificial red blood cells (RBC'S): preliminary but very promising.
Analysis of: Scientists Find Way to Create Red Blood Cells | online.wsj.com
Author: GLG Expert Contributor
Advanced Cell Technology in Worcester, Mass., the University of Illinois at Chicago and the Mayo Clinic in Rochester, Minn. scientists say they've found an efficient way to make red blood cells from human embryonic stem cells. Impreesive!
August 21, 2008
Cervical Cancer Vaccines: Hope or Hype?
Analysis of: Drug Makers’ Push Leads to Cancer Vaccines’ Fast Rise | www.nytimes.com
Author: GLG Expert Contributor
Cervical cancer vaccines manufactured by Merck and Glaxo have been hyped, pushed and if the companies have their way, mandated by various states and organizations. (Who is benefiting? Patients or the politicians?) There are many unanswered questions but marketing and mandates press on!
August 20, 2008
Sunitinib vs Interferon: No contest at the onset
Analysis of: Economic Evaluation of Sunitinib Malate for the First-Line Treatment of Metastatic Renal Cell Carcinoma | jco.ascopubs.org
Author: GLG Expert Contributor
When using a model (of whose desin?) Pfizer's Sunitinib (Sutent) was found to be cost effective by Pfizer people? Surprise!!!
August 19, 2008
Cole & Pfizer: Happy together in NSCLCA (non small cell lung cancer)
Analysis of: Randomized Phase II Trial of a Toll-Like Receptor 9 Agonist Oligodeoxynucleotide, PF-3512676, in Combination With First-Line Taxane Plus Platinum Chemotherapy for Advanced-Stage Non–Small-Cell Lung Cancer | jco.ascopubs.org
Author: GLG Expert Contributor
"The investigator-assessed objective response rate (complete and partial response), including both confirmed and unconfirmed responses, was 38% in the PF-3512676 plus chemotherapy arm and 19% in the chemotherapy-alone arm (P = .043)." In other words. IT MAY WORK!
August 13, 2008
"Health-care costs are expected to rise more than 10% ".... and we can continue this for how long??
Analysis of: Insurers Expect Health-Care Costs To Rise More Than 10% Next Year | online.wsj.com
Author: GLG Expert Contributor
10% increase in medical spending when the overall cost of living is 1/2 of medical costs and we are happy??
August 11, 2008
Fair or Unfair Decision: the cost of the drugs for kidney cancer is more than the economy can bear.
Analysis of: UK Says Kidney Cancer Drugs Are Too Pricey | www.pharmalot.com
Author: GLG Expert Contributor
Pfizer’s Sutent, Wyeth’s Torisel, Bayer’s Nexavar and Avastin, sold by Roche and Genentech have been deemed too expensive to be paid for by UK agencies
August 7, 2008
Salmonella; Cancer cells?? Let's not get carried away
Analysis of: Salmonella Is Tested To Fight Cancer Cells | online.wsj.com
Author: GLG Expert Contributor
Salmonella targeting cancer cells? In humans???
August 6, 2008
Boy will this p.... off Urologists as well as AARP!
Analysis of: Panel Urges End to Prostate Screening at Age 75 | www.nytimes.com
Author: GLG Expert Contributor
Since treatment may be worse than the disease it is being recommended that routine prostate cancer screening be stopped after the age of 75.

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