Analysis of:
8-Year-Olds on Statins? A New Plan Quickly Bites Back (www.nytimes.com)
The potential market for treatment of lipids(cholesterol)continues to grow. Recent recommendations regarding potential for treatment of children as young as 8 are controversial, primarily because of the lack of data to demonstrate efficacy in terms of "hard" endpoints(i.e. mortality/MI)vs. morbidity...
Analysis of:
Patients Curb Prescription Spending (online.wsj.com)
Given the economic pressures on patients, they are now more likely to ask for generic medications than they were in the past. Given that there are generic versions of several classes of medications, physicians such as me are more likely to comply with a patient's request for a generic than in...
Analysis of:
Drugs to Build Bones May Weaken Them (www.nytimes.com)
Patients may ask about this. Haven't heard anyone yet.
Analysis of:
Medicare Bil Includes e-Prescribing Bonus (www.modernhealthcare.com)
Medicare will use a very small carrot to entice financially stressed physicians to employ electronic prescribing technology. Later on, Medicare will switch to the stick and penalize physicians who don't use such a system.
Analysis of:
Bill to Block Medicare-Fee Cuts (online.wsj.com)
Cuts in Medicare put off for the time being, though only under substantial political pressure. This band-aid will last only so long; real reform of the flawed sustainable growth rate eludes us yet again! Bush and friends still favor the insurance lobby over senior's access to their phys...
Analysis of:
Drug Makers Say FDA Safety Focus Is Slowing New-Medicine Pipeline (online.wsj.com)
Drug makers complain that the FDA's 'safety focus' slows down their development of new medications. They would love to see accelerated approvals; next they'll get the immunity from lawsuits that device makers have already received!
Analysis of:
Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Total Knee Arthroplasty (content.nejm.org)
The major impact of this article is that if a strategy of longer term prophylaxis is employed (6 weeks vs in hospital) that better outcomes will be seen in DVT prevention after TKA and THR. While the drugs work differently, the difference in duration of treatment likely explains all of the difference...
Analysis of:
Doctors Say Medication Is Overused in Dementia (www.nytimes.com)
Many times, nursing homes will call doctors practically demanding some sort of medicne for delusional or combative patients. They will even suggest medicines by name. Often, these phone calls occur at 3:00 AM, and the doctor gives a quick yes to give them an answer and get back to sleep....
Analysis of:
FDA Panel To Weigh Heart Trials For Diabetes Meds (www.pharmalot.com)
“A requirement for demonstrating cardiovascular benefit will likely have major implications on the availability of new treatments for type 2 diabetes, because conclusive evidence of a reduced risk of macrovascular complications in type 2 diabetes has not yet been established for any of the currently...