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Sunil DhawanMarch 19, 2007
Portrait Plasma technology by Rhytec
Analysis of: Blast Away Wrinkles | www.ivanhoe.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This technology is new, but no better than other resurfacing technologies like Sciton and Fraxel. Pain is significant, healing takes weeks, and there are risks as in other resurfacing technologies. The final results are good. A head to head comparison with other technologies is needed.  
Sunil DhawanMarch 12, 2007
Excessive antibiotic use leads to resistance
Analysis of: Proof Nailed Down that Antibiotics Use Leads to Resistance | www.medpagetoday.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article has validity in dermatology due to the increased resistance seen in acne. This may have clinical significance in that we may be seeing resistance to therapy in acne patients  after prolonged use.Collagenex corp. is developing non antibiotic medications for acne and rosacea that are...
Sunil DhawanMarch 8, 2007
Relieva results are encouraging
Analysis of: Allegiance Equity Corporation Announces Positive Results of In Vitro Studies and an Open Label Trial for Relieva(R) in Treating Atopic Dermatitis | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
The open label trial results for the product Relieva from Allegiance Equity Corp. are encouraging. However the trials need to be double blinded, and with a much larger number of patients. If the product can be compared to a low- mid potency topical steroid in efficacy, then it will be successful. Homeopathic...
Sunil DhawanMarch 8, 2007
Alitretinoin results positive in Hand dermatitis
Analysis of: Basilea Reports Positive Phase III Results for Alitretinoin | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This large phase 3 trial for Alitretinoin results are significant in the this would be the first oral agent specifically for resistant hand dermatitis. the results are positive with good significance. The major problem will be getting the FDA  to accept the drug without the onerous pregnancy prevention...
Sunil DhawanFebruary 27, 2007
Topical anesthetics are dangerous if used incorrectly
Analysis of: Excessive Use of Topical Anesthetics Can Be Fatal | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Compounded topical anesthetics can have dangerous side effects if used inappropriately over large surface areas, large amounts, under occlusion, for long periods, etc. Rational, supervised use is safe and very helpful in controlling pain in many outpatient laser and other procedures
Sunil DhawanFebruary 27, 2007
Switching Retinoids during acne therapy does improve outcomes
Analysis of: No Need to Switch Retinoids During Acne Vulgaris Treatment | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This poster at the 2007 American Academy of Dermatology meeting in Washington, DC indicates that Galderma's product, Adapalene, is as effective as Allergan's product Tazarotene. This is opposite to 2 other studies that have been done in the past indicating that Tazarotene is the most effective retinoid,...
Sunil DhawanFebruary 26, 2007
Obagi Medical Products Clenziderm should have a positive impact
Analysis of: Obagi Medical Products, Inc. Launches CLENZIderm M.D. Penetrating Acne Therapeutic System | www.pharmalive.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Obagi Medical Products Clenziderm should have a positive impact:1. It allows the physician or the medical aesthetician under the physician’s guidance to dispense an effective product without a prescription.2. Its efficacy may approach that of prescription products, and studies are needed to confirm...
Sunil DhawanFebruary 26, 2007
Ceragenix Epiceram product has good potential to be effective in eczema and other skin conditions
Analysis of: Ceragenix Completes Patient Visits for EpiCeram Clinical Study | www.pharmalive.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Ceragenix's new product Epiceram, the Barrier repair cream has potential merit and efficacy comparable to mid strength topical steroids:1. Barrier repair has been found to be antiinflammatory.2. The product in mouse studies has effects comparable to steroid creams.3. The product will have less/ minimal...
Sunil DhawanFebruary 26, 2007
CNTO 1275 will have an impact on the psoriasis market
Analysis of: Centocor, Inc. Releases Phase 2 Data on Novel Biologic CNTO 1275 Targeting Chronic Plaque Psoriasis | pharmalive.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Centocor's product CNTO1275 will have a major and sustained impact on the market:1. Its PASI 75 reduction is better than the current injectables other than Centocor's Infliximab, which requires a complicated IV infusion.2. Side effects are comparable to other agents.3. It is specifically being developed...
Sunil DhawanFebruary 26, 2007
Will the OTC laser hair systems have an impact??
Analysis of: Palomar and Gillette Expand Their Collaboration to Develop and Commercialize an Additional Light-Based Hair Removal Device for Home Use | phx.corporate-ir.net
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Implications: Palomar and Gillette’s venture in the direct to consumer sale of a light based laser device has several issues that will effect the ability of this venture to be successful 1. The device is only approved for non facial areas, and is only temporarily effective with less than 10% reduction-...

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