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GLG News by General Internal Medicine Physicians (US)

Analysis of: Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair (www.pipelinereview.com)
Ever since Hyaluronans (HA) have been around to lubricate the the knee, arthroplasties have declined significantly for OA. This implies that finding the precise material necessary to keep the knee capsule full will prevent further degeneration of the joint and eventually the ultimate answer to treat...
October 29, 2007
Not Surprised
Analysis of: U.S. veterans dept to limit Glaxo's Avandia: report (www.reuters.com)
In spite of GSK's best efforts, I am feeling the vibes, both in myself and in those doctors around me, that damage control is not working.  I just attended a Teleconference with C. Beck the other night, and the moderator soundly trounced Avandia, even allowing for his being paid to speak for Takeda's...
Analysis of: Galvus(R) receives European approval as new treatment for type 2 diabetes with broad range of indications (www.pipelinereview.com)
Galvus is now approved for use in all 27 countries of the European Union, plus Norway, Iceland, Brazil, and Mexico.  It is the first in it's class to be approved for combination therapy with all three of the most commonly prescribed oral diabetic agents--metformin, sulfonyureas,...
September 24, 2007
A Winner, maybe...
Analysis of: Electronic Prescription Drug Act of 2007 (www.thomas.loc.gov)
I tracked down the proposed law online, and seems to still be in a very rough draft state;  I find it hard to believe that a doctor will be paid $1.00 per electronic prescription.  That can actually add up to a lot of money per month, and actually make me NOT groan when, at the end of a visit,...
Analysis of: Health Insurers Mull Costs, Future of Medicare (www.thestreet.com)
Health insurance margins are declining.  The old model of increasing premiums or lowering health care costs is not enough to sustain profitability.  As a physician I see both sides of the 3rd party payor equation and a new model must be created to maintain profits.  There is increasing...
July 26, 2007
An Ominous Trend
Analysis of: An Innovation in Health Care Opens at CVS/Pharmacy Stores in Knoxville and Chattanooga (money.cnn.com)
This seems to me, as a board certified practicing Internist, as yet another intrusion into the successful continuing concept of private practice.  As Internists, we don't just treat Lupus, heart failure, renal failure, strokes, etc.  Those conditions do require our skill and training levels,...
Analysis of: Pfizer’s Lyrica Receives FDA Approval for Fibromyalgia (home.businesswire.com)
Something actually indicated for this disease.
Analysis of: Shire Receives Approvable Letter from FDA for INTUNIV(TM) (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD (www.pipelinereview.com)
Alternative drug to use.  Lower abuse potential  Lower stigma
Analysis of: The U.S. Food and Drug Administration Approves New Actonel Dose to Treat and Prevent Postmenopausal Osteoporosis (phx.corporate-ir.net)
Compliance issues  ? side effects
November 20, 2006
Free at last!
Analysis of: Bayer and Ortho-McNeil, Inc. Outline Phase III Study Program of Oral Factor Xa Inhibitor Rivaroxaban in Chronic Indications (www.pipelinereview.com)
An oral anticoagulant that does not require monitoring.

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