Analysis of:
C. Difficile And Antibiotics Not Necessarily Linked, Study Finds (www.sciencedaily.com)
This study did not conclude that antibiotic use does not precipitate C. difficile infections. What it found was that the individuals who are infected with C. diff did not necessarily take antibiotics in the six weeks preceding their infection. In my mind, rather than demonstrating that C....
Analysis of:
Protecting a Home From Silent Threat (www.nytimes.com)
Yes, there are elevated radon levels in some homes, and, yes, there are patients with lung cancer in some homes, as well. But the connection, while it might be intuitive, remains to be solidified.
Analysis of:
FDA urged to recall cold medicines for youngsters (news.yahoo.com)
There is a alot of information in the media about the dangers of givng OTC cough medication to young children . Many children have ended up in the emergency room after "over-ingesting" "cold remedy products that include OTC antihistamines, decongestants and cough suppressants. Also when...
Analysis of:
Parents 'need lessons about ADHD (news.bbc.co.uk)
The well-regarded Multimodal Treatment study (MTA Study) has shown that adjunctive, behavioral treatment alone is not as effective as treatment options which include medications. Parent input (and education), however, is critical for day-to-day management of these children, since the parents are on...
Analysis of:
Many Trial Reports on FDA-Approved Drugs Go Unpublished (www.washingtonpost.com)
This study looked at drugs that were eventually approved by the FDA, and found that only 43% of early phase (non-"pivotal") trials were published in the medical literature. But imagine what this means for drugs that ultimately fail: if drugs that are destined for success are withholding 57% of...
September 25, 2008Why Not?
Analysis of:
Lilly to Disclose Payments to Doctors (online.wsj.com)
As physicians, we should have nothing to hide when we provide unbiased advice to pharmaceutical companies. Receiving a grant (or a lunch or a free pen) does not, for the vast majority, obligate us to be anything other than concerned for our patients, first and foremost.
Analysis of:
ACE Inhibitor May Ease Cardiac Risks in Marfan's Syndrome (www.medpagetoday.com)
In this small and short-duration study, ACE inhibitors seem to provide an additional preventive benefit when used with beta blockers in patients with marfan's syndrome. This is all to the good for those patients, and if the results of this preliminary study are borne out over a longer term, this may...
Analysis of:
Europe adopts new pediatric drug rule (www.nationalreviewofmedicine.com)
Children have long been therapeutic orphans, often relying on off-label use of new drugs which have only been tested on adults. This legislation seeks to remedy that inequality, by encouraging pharmaceutical companies to do more testing in pediatric populations.
Analysis of:
Abbott signs deal to promote Crestor in U.S. (www.chicagotribune.com)
With Abbott being such a major player in the infant formula market, will this lead to more promotion of statins in the pediatric office, especially given the recent (although controversial) recommendation for possible statin use in children as young as 8 years old? And since they are involved in the...
Analysis of:
Drug Makers’ Push Leads to Cancer Vaccines’ Fast Rise (www.nytimes.com)
Cervical cancer is real, and has the potential to cause significant morbidity and mortality. Yet the incidence in developed countries is relatively small, when compared with the developing world. There is a real, although small, benefit in the US, and while the vaccine is effective, the cost per prevented...
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