GLG News by Diovan Prescribers: Cardiologists
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August 6, 2008
Statin therapy for children
Analysis of: 8-Year-Olds on Statins? A New Plan Quickly Bites Back | www.nytimes.com
Author: GLG Expert Contributor
Analysis of: 8-Year-Olds on Statins? A New Plan Quickly Bites Back | www.nytimes.com
Author: GLG Expert Contributor
The potential market for treatment of lipids(cholesterol)continues to grow. Recent recommendations regarding potential for treatment of children as young as 8 are controversial, primarily because of the lack of data to demonstrate efficacy in terms of "hard" endpoints(i.e. mortality/MI)vs. morbidity...
July 30, 2008
Reduction of systolic pressure decreases cognitive decline in susceptible individuals.
Analysis of: Blood pressure drugs may protect against Alzheimer's | www.washingtonpost.com
Author: GLG Expert Contributor
Analysis of: Blood pressure drugs may protect against Alzheimer's | www.washingtonpost.com
Author: GLG Expert Contributor
Over the past 15 years there have been several long-term trials which have provided evidence that reduction of systolic pressure in an elderly population prevents the cognitive decline associated with ageing. The most recent studies have demonstrated the prevention of Alzheimer's-like symptoms. These...
July 7, 2008
Complicated issue
Analysis of: Doctors Say Medication Is Overused in Dementia | www.nytimes.com
Author: GLG Expert Contributor
Analysis of: Doctors Say Medication Is Overused in Dementia | www.nytimes.com
Author: GLG Expert Contributor
Many times, nursing homes will call doctors practically demanding some sort of medicne for delusional or combative patients. They will even suggest medicines by name. Often, these phone calls occur at 3:00 AM, and the doctor gives a quick yes to give them an answer and get back to sleep....
June 23, 2008
Doctors don't profit from EHRs
Analysis of: Most Doctors Aren’t Using Electronic Health Records | www.nytimes.com
Author: GLG Expert Contributor
Analysis of: Most Doctors Aren’t Using Electronic Health Records | www.nytimes.com
Author: GLG Expert Contributor
Third party payers benefit the most from EHRs because it makes charts easier to audit The cost of implementing an EHR is excessive for a small practice of 2-5 physicians.
May 28, 2008
obviously works better
Analysis of: New data show Tekturna HCT® is twice as effective at reducing blood pressure than the diuretic HCT alone | www.novartis.com
Author: GLG Expert Contributor
Analysis of: New data show Tekturna HCT® is twice as effective at reducing blood pressure than the diuretic HCT alone | www.novartis.com
Author: GLG Expert Contributor
The info that tekturna HCT works twice as well as HCTZ alone is not earth shattering. Of course it's better. That can be said of any HCT/medicine combination
May 27, 2008
Promising results for tekturna
Analysis of: New data show Tekturna HCT® is twice as effective at reducing blood pressure than the diuretic HCT alone | www.novartis.com
Author: GLG Expert Contributor
Analysis of: New data show Tekturna HCT® is twice as effective at reducing blood pressure than the diuretic HCT alone | www.novartis.com
Author: GLG Expert Contributor
Novartis was able to show that combining tekturna with HCTZ provided significant improvement in blood pressure and did so safely. They also showed that it provides better 24 hour coverage and coverage if patients miss a dose or take it late, this is a significant improvement over its competitors...
February 19, 2008
Need for cardiac evaluation in patients receiving novel cancer treatments
Analysis of: Kidney Cancer Drug Linked to Higher Rate of Heart Problems | www.washingtonpost.com
Author: GLG Expert Contributor
Analysis of: Kidney Cancer Drug Linked to Higher Rate of Heart Problems | www.washingtonpost.com
Author: GLG Expert Contributor
Patients with rare malignancies, especially those with already metastatic diseases, are being treated with novel oncologic agents. However, as is being seen with many drugs, the hemodynamic consequences of these agents, in many cases a rise in blood pressure, may lead to cardiovascular consequences. ...
January 18, 2008
Outsourcing of compassionate use of drugs?
Analysis of: No right to experimental drugs for dying patients: Supreme Court | news.yahoo.com
Author: Dan Streja, Clinical Professor of Medicine, University of California, Los Angeles
Outsourcing of compassionate use of drugs?
Analysis of: No right to experimental drugs for dying patients: Supreme Court | news.yahoo.com
Author: Dan Streja, Clinical Professor of Medicine, University of California, Los Angeles
The Supreme Court has rejected the use of experimental drugs by the dying patients on the grounds that "The framers (of the US constitution) understood that the pursuit of life is an inalienable right that should not be abridged without due process of law." Over the years our patients with terminal...
December 19, 2007
Frivolous patent chanlleges: is there a reasonable solution?
Analysis of: AstraZeneca Files Patent Infringement Actions in Response to Crestor(TM) ANDAs | www.pipelinereview.com
Author: GLG Expert Contributor
Analysis of: AstraZeneca Files Patent Infringement Actions in Response to Crestor(TM) ANDAs | www.pipelinereview.com
Author: GLG Expert Contributor
Challenges to pharmaceutical patents prior to the "official" expiration of the patent are proliferating; if they are allowed to stand, that is, if the "original" patent is successfully voided one of the crucial financial incentives to novel pharmaceutical research will be abridged and the "profit" motive...
November 22, 2007
You can never get something for nothing!
Analysis of: Study Shows Weight-Loss Drug Rimonabant is Associated with Severe Adverse Psychiatric Events | pharmalive.com
Author: GLG Expert Contributor
Analysis of: Study Shows Weight-Loss Drug Rimonabant is Associated with Severe Adverse Psychiatric Events | pharmalive.com
Author: GLG Expert Contributor
The meta-analysis of the rimonabant trials points to an increase in psychiatric diagnoses. What is missing in this report is the numberical and statistical significance of the findings. This debate needs more rigor; the type of rigor that is applied to cardiac endpoints, needs to be applied here. ...
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Off Label Use Can Be Prevented
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Gardasil will most certainly be approved for boys
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