GLG News by Dermatologists (US)

For too long Allergan has monopolized the therapeutic and cosmetic market of botulinum toxin type A, and has taken full advantage of that monopoly by raising the price of Botox almost biannually. Reloxin studies are very favorable when compared to Botox, and may even surpass it in one or two aspects....

 The submission of Reloxin to the FDA is a positive sign for both Ipsen and Medicis. The market will only grow with the impending approval, and the launch of a competitor to Botox may result in some softening of pricing both to physicians and the end consumer. The two studies that have been done...

Meyer Pharmaceutical acquisition of a NF-kB decoy is interesting in that this would be the first new technology in this area since the topical immunomodulators like Protopic/ Elidel were released. The preliminary work looks good, and phase 2 trials in both atopic dermatitis and psoriasis would be necessary...

CombinatoRx new combination product- CRx-191 is intriguing in that it combines a topical steroid with nortryptiline to minimize the negative effects of the steroid and make it more potent. This would be useful in that higher potency topical steroids are more effective, but cause more thinning of the...

The recently announced collaboartion between Stiefel and Allergan in regards to Tazorac is very positive. Stiefel needs this molecule to put into different dosage forms, and in combination with its existing products espoecially Duac, etc. Their current acne product line is strong, but this will solodify...

Why bother with this branded 2% hydrocortisone lotion?  Likely third tier, and nothing special other than the gimicky wash that goes along with it.  The lotion is a very weak %of steroid- so probably minimally useful. ? pediatric indication, would possibly have some hope for the product.

This is an absurdity. 

Abbotts ABT-874 monoclonal antibody for psoriasis shows impressive results in the phase 2 trial. The results were up to 90% of patients achieving at least 75% reduction in their psoriasis. These results are as good or better than those with Remicade the most effective biologic for psoriasis currently....

The recent results for a trial of Relieva in atopic dermatitis or eczema, a cream containing a homeopathic compound, were positive by a report from the company. The study sample was small, and the trial was open label. Generally these trials have a larger number of patients, and are blinded. Also it...

This treatment is run illegally, in violation of FDA laws Additionally, it is outlawed in Europe, Canada and Brazil, among other places Lastly, it isn't all that effective, from what I hear, and very painful.  In summary, better options will become available.