GLG News by Cosmetic Dermatologists in Private Practice (US)
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March 23, 2007Gadolinium agents linked to NFD
Analysis of: Nephrogenic Fibrosing Dermopathy Associated with Exposure to Gadolinium-Containing Contrast Agents | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This and other studies are highly suggestive that Gadolinium agents used in radiographic studies are associated with NFD. A large scale study should be initiated to confirm this association, and for now these agents should be avoided in patients with renal disease.
March 23, 2007The Black box warning of the Calcineurin inhibitors is faulty
Analysis of: Black Box Warning for Topical Calcineurin Inhibitors and the Death of Common Sense | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
I totally agree with this article. The conclusions from the FDA are incorrect, and the data appear to indicate that the TCI's are actually protective!!!! In any event it has created a false sense of a problem, where none exists, and decreases the use of these agents, which are safer than the existing...
March 23, 2007Acne scarring an under treated condition
Analysis of: Treatment of Acne Scarring | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article is a good summary of the currently available techniques of excision, subcision, and resurfacing. It does not mention dermal grafting, a technique that I personally use quite often. The maximum correction that one can achieve is 50-70% with a combination of multiple techniques.
March 19, 2007Cytochroma Cta018 cream
Analysis of: Cytochroma Completes Enrollment In Phase II Psoriasis Trial | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This product by Cytochroma is a vitamin D analog which is similar to Dovonex, a product that has been used for 13 years. Its efficacy is modest at best. This product may, repeat may be better, because it activates the vitamin D pathway, and inhibits catabolism of Vitamin D. Whether this makes the product...
March 19, 2007Portrait Plasma technology by Rhytec
Analysis of: Blast Away Wrinkles | www.ivanhoe.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This technology is new, but no better than other resurfacing technologies like Sciton and Fraxel. Pain is significant, healing takes weeks, and there are risks as in other resurfacing technologies. The final results are good. A head to head comparison with other technologies is needed.
March 12, 2007Excessive antibiotic use leads to resistance
Analysis of: Proof Nailed Down that Antibiotics Use Leads to Resistance | www.medpagetoday.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article has validity in dermatology due to the increased resistance seen in acne. This may have clinical significance in that we may be seeing resistance to therapy in acne patients after prolonged use.Collagenex corp. is developing non antibiotic medications for acne and rosacea that are...
March 8, 2007Relieva results are encouraging
Analysis of: Allegiance Equity Corporation Announces Positive Results of In Vitro Studies and an Open Label Trial for Relieva(R) in Treating Atopic Dermatitis | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
The open label trial results for the product Relieva from Allegiance Equity Corp. are encouraging. However the trials need to be double blinded, and with a much larger number of patients. If the product can be compared to a low- mid potency topical steroid in efficacy, then it will be successful. Homeopathic...
March 8, 2007Alitretinoin results positive in Hand dermatitis
Analysis of: Basilea Reports Positive Phase III Results for Alitretinoin | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This large phase 3 trial for Alitretinoin results are significant in the this would be the first oral agent specifically for resistant hand dermatitis. the results are positive with good significance. The major problem will be getting the FDA to accept the drug without the onerous pregnancy prevention...
February 27, 2007Topical anesthetics are dangerous if used incorrectly
Analysis of: Excessive Use of Topical Anesthetics Can Be Fatal | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Compounded topical anesthetics can have dangerous side effects if used inappropriately over large surface areas, large amounts, under occlusion, for long periods, etc. Rational, supervised use is safe and very helpful in controlling pain in many outpatient laser and other procedures
February 27, 2007Switching Retinoids during acne therapy does improve outcomes
Analysis of: No Need to Switch Retinoids During Acne Vulgaris Treatment | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This poster at the 2007 American Academy of Dermatology meeting in Washington, DC indicates that Galderma's product, Adapalene, is as effective as Allergan's product Tazarotene. This is opposite to 2 other studies that have been done in the past indicating that Tazarotene is the most effective retinoid,...
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Source Article | Expert Analyses
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Personal medicine is goal of Eli Lilly & Co.
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Use of Antipsychotics in Children Poses Risks of Adverse Effects
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Off Label Use Can Be Prevented
November 24, 2008
Gardasil will most certainly be approved for boys
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