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GLG News by Corrective Refractive Laser Surgeons (US)

January 28, 2008
NO SURPRISE.
Analysis of: 19 Percent of Office-Based Physicians Refuse to See Pharmaceutical, Biotech and Medical Device Sales Reps (www.drugs.com)
MOST TEACHING HOSPITALS LOOK DOWN THEIR ACADEMIC NOSE AT ANYTHING COMMERICAL. THESE SAME SCHOOLS DON'T TEACH DOCTORS HOW TO SURVIVE MUCH LESS SUCEED IN THE PRIVATE SECTOR.
Analysis of: Allergan, Inc. Receives FDA Approval For COMBIGAN™ (Brimonidine Tartrate/timolol Maleate Ophthalmic Solution) 0.2%/0.5% (www.medicalnewstoday.com)
Combigan is a glaucoma medication which combines a beta blocker and alpha agonist. Although combination drugs are great for glaucoma management, this will NOT be a first line medication in treating glaucoma.  The prostaglandins (PFE, ACL) are still the gold standard IOP lowering agents...
Analysis of: Allergan, Inc. Receives FDA Approval For COMBIGAN™ (Brimonidine Tartrate/timolol Maleate Ophthalmic Solution) 0.2%/0.5% (www.medicalnewstoday.com)
The market for eye drops for the treatment of open angle glaucoma is huge. Profit potential for pharmaceutical companies, however, is limited by the time period that they are afforded patent protection. Combigan, the just approved brimonidine/timolol combination therapy, affords Allergan new patent...
Analysis of: Allergan, Inc. Receives FDA Approval For COMBIGAN™ (Brimonidine Tartrate/timolol Maleate Ophthalmic Solution) 0.2%/0.5% (www.medicalnewstoday.com)
Patient compliance with glaucoma eyedrops is a key barrier in achieveing acceptable clinical outcomes. There is only one other product, Cosopt (by Merck) that offers a combination glaucoma medication. This medication may become a popular choice for glaucoma doctors to improve patient complian...
Analysis of: Genentech revisits plan for Avastin (www.sfgate.com)
In the two weeks since Genetech made its announcement that it would limit the availability of Avastin to ophthalmologists for use in treating wet macular degeneration the outcry from patients, ophthalmologists, politicians, and the American Academy of OPhthalmology has been so great that Genetech is...
Analysis of: Visual performance of patients with bilateral vs combination Crystalens, ReZoom, and ReSTOR intraocular lens implants (www.ncbi.nlm.nih.gov)
IOL technology has improved dramatically over the past decade.  However, the current multifocal/accommodating lenses (i.e., ReSTOR, ReZoom, and Crystalens) each have their own strengths and weaknesses.  The topic of matching or mixing lenses has therefore become very important.
Analysis of: Ophthalmologists Concerned About AMD Patients’ Access To Avastin (aao.org)
The American Academy of Ophthalmology said the recent decision by Genentech to limit availability of Avastin (bevacizumab) to compounding pharmacies could have a significant negative impact on the care of patients with age-related macular degeneration [AMD]. Dr. Charles Wilkinson, president of the AAO,...
Mark Packer, MD, Clinical Associate Professor of Ophthalmology
Mark Packer, MD, Clinical Associate Professor of Ophthalmology
OREGON HEALTH & SCIENCE UNIVERSITY - CC
Analysis of: Visual performance of patients with bilateral vs combination Crystalens, ReZoom, and ReSTOR intraocular lens implants (www.ncbi.nlm.nih.gov)
Presbyopia correcting IOLs currently represent 5% of all IOLs implanted in the United States (about 3.5 million per year).  The products available in this category include the ReSTOR multifocal IOL (Alcon), the ReZoom multifocal IOL (AMO) and the cyrstalens accommodative IOL (eyeonics).  Although...
Analysis of: Genentech to cease supplying bevacizumab to compounding pharmacies (www.osnsupersite.com)
Genentech, Inc.  is suspending sales of Avastin (bevacizumab) to compounding pharmacies in the United STates, in an effort to curb its non approved use for wet macular degenration. Recently, ophthalmologists have begun using the antiangiogenic cancer drug off-label to treat retinal neovascularization...
Analysis of: Alacrity Biosciences Announces Positive Results from a Phase 2 Study of Its Dry Eye Treatment ALTY-0501 (www.pipelinereview.com)
Alacrity Biosciences has completed a Phase 2 clinical trial of ALTY-1501, an eye drop for the treatment of dry eye. Dry eye (or keratoconjunctivitis sicca (KCS) affects more than 10% of the US population and its incidence is increasing as baby boomers become senior citizens. Although the small...

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