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GLG News by Cornea Specialists (US)

Analysis of: Genentech to cease supplying bevacizumab to compounding pharmacies (www.osnsupersite.com)
Genentech, Inc.  is suspending sales of Avastin (bevacizumab) to compounding pharmacies in the United STates, in an effort to curb its non approved use for wet macular degenration. Recently, ophthalmologists have begun using the antiangiogenic cancer drug off-label to treat retinal neovascularization...
Analysis of: Microsoft launches Web site to hold medical records (uk.reuters.com)
This move by Microsoft has brought attention to a vast untapped field of personal medical information being saved online. It promises the convenience factor as well as privacy sought after by the patients. Making its foray into this field with two well thought acquisitions by Microsoft, this website...
Analysis of: IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth (www.pnas.org)
Omega-3 supplementation could be a useful strategy for protecting against retinopathy of prematurity (ROP), say Swedish investigators. In the study, mice with retinopathy were fed food enriched with either omega-3 or omega-6. Mice that ate omega-3 initially lost fewer retinal blood vessels than mice...
Analysis of: Blood Pressure, Arterial Stiffness, & Open Angle Glaucoma: The Rotterdam Study (archopht.ama-assn.org)
Patients with high arterial pulse pressure may be at increased risk for high-tension open angle glaucoma, a Dutch study concludes. Researchers analyzed data from 5,317 individuals, 215 of who had definite or probable open-angle glaucoma and 5,102 of whom were disease free.The analysis found that high-tension...
Analysis of: Ophthalmic business: Alcon exceeds 70% stake in WaveLight (www.osnsupersite.com)
Alcon holds more than 70% of Wavelights shares and its takeover of Wavelight has been approved by the German authorities. WHile wavelight produces some interesting intraocular lenses, it is clear that Alcons interest in Wavelight lies in its realiable and fast excimer laser system that can be used for...
Analysis of: Targeting amyloid- b in Glaucoma (www.pnas.org)
New research indicating the presence of amyloid-beta protein in dying retinal cells  suggests a new direction in glaucoma research. Amyloid-beta is a protein found in Alzheimer's plaques. Using a rat model of glaucoma, the researchers found that the dying retinal cells showed accumulation of amyloid-beta....
Analysis of: Aussie Boxing Champion Hospitalized Due To Eye Infection; Doubts About Career Prospects (www.allheadlinenews.com)
Boxer Sugar Ray Leonard had a complex retinal detachment, Orlando Brown of football was nearly blinded by a referee's thrown flag.  Soft contact lens wear is barely compatible with sweaty, dusty contact sports. Some great basketball players wore (& wear) goggles.  Asking boxers to wear...
Analysis of: Tears in the Retinal Pigment Epithelium: A Complication Associated with the New Macular Degeneration Treatments (pt.wkhealth.com)
Tears of the retinal pigment epithelium (RPE) may develop during the course of anti-VEGF therapy for age-related macular degeneration (AMD) related pigment epithelial detachment (PED), according to a study published in the June issue of Retina.  A total of 33 cases of RPE tear after treatment with...
Paul Chen, MD, Ophthalmologist
Paul Chen, MD, Ophthalmologist
North County Laser Eye Associates
Analysis of: New Method Of Adult Stem Cell Growth Treats Cornea Disorders (www.sciencedaily.com)
I have been working on a cell transfer device designed to optimize wound healing after PRK laser vision correction. Essentially, we plan to coat a silicone hydrogel contact lens with a thin dissolvable layer of collagen on the concave surface. Cultured epithelial cells would be seeded onto the collagen...
Analysis of: FDA Accepts Jerini Ophthalmic's IND of JSM 6427 for the Treatment of AMD (www.pipelinereview.com)
This article describes a new drug that has a potential to address pathophysiology of wet macular degeneration on broader basis than treatments we use currently. This drug inhibits not only angiogenesis but also fibrosis formation and inflammation which remain a significant problem even with successful...

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