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GLG News by Cardiologists who Implant Cardiopulmonary Support

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January 25, 2008
Preventing Bariatric Surgery Deaths
Analysis of: Pinning Down Mortality Rates After Bariatric Surgery | www.medscape.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
 Bariatric surgery is a major operative procedure that caries significant morbidity and mortality risks due to the comorbid diseases seen in this patient population.  This procedure is increasing in frequency as more patients are willing to have it and more surgeons are becoming proficient. The...
August 28, 2007
CMS regulations penalize hospitals for taking care of sickest patients
Analysis of: New Medicare Regulations Adopted To Reduce Certain Hospital Infections And Medical Errors | www.medicalnewstoday.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
This article presents the new CMS guidelines that deny higher payments for the additional costs associated with treating patients for certain hospital - acquired infections and medical errors. While these are laudable goals, to assume that all infections are the result of poor medical practice is an...
August 28, 2007
Retail drugstore clinics - filling a niche ?
Analysis of: Drugstore Clinics Spread, and Scrutiny Grows | www.nytimes.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Several large drugstores are establishing retail medical clinics within their stores much as eyeglass stores have had optomitrists on site.  There is no problem with these clinics per se as long as they practice within the scope of the practitioners license and skill.  There are...
August 28, 2007
The drug patent "shell game"
Analysis of: New antihistamine gets FDA green light.(RX CARE)(Levocetirizine (Xyzal) by UCB Inc. and Sanofi-Aventis ) | www.therapeuticsdaily.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Zyrtec (cetirizine) is a second generation nonsedating antihistamine that has enjoyed wide popularity.  Zyrtec will become available generically in late 2007 and the generic form is expected to be significantly cheaper.  To virtually extend the patent, the manufacturer is...
August 21, 2007
FIRE STAR™ Rx PTCA Dilatation Catheter - an incremental improvement, not disruptive technology
Analysis of: Cordis Corporation Introduces FIRE STAR™ Rx PTCA Dilatation Catheter | www.medicalnewstoday.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Cordis introduced the FIRE STAR™ Rx PTCA Dilatation Catheter to the European market.  This catheter reportedly has a lower profile than other devices on the market which enables it to cross highly stenotic or tortuous lesions.  There are no controlled studies showing device...
July 6, 2007
Bariatric surgery is a useful adjunct in the management of obese diabetics
Analysis of: Bariatric surgery - possible treatment for type 2 diabetes mellitus | www.news-medical.net
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Type II diabetes and the metabolic syndrome are highly correlated with obesity. These diseases are epidemic in our society.  Weight loss has been definitively shown to reduce morbidity and mortality in these patients with complications from their obesity.  Bariatric surgery is...
July 6, 2007
Non-stimulant treatment for ADHD - a new alternative
Analysis of: Shire Receives Approvable Letter from FDA for INTUNIV(TM) (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD | www.pipelinereview.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Shire PLC received an approvable letter from the FDA for its nonstimulant treatment for ADHD - Intuniv (guanfacine)   Most of the treatments for ADHD are stimulants (amphetamine derivatives) that can have potentially serious cardiovascular side effects. Unfortunately, to date,...
July 6, 2007
Rimonabant - the FDA gets it wrong.......Again
Analysis of: FDA Advisory Committee Did Not Recommend Approval of Rimonabant (ZIMULTI(R)) for Use in Obese and Overweight Patients With Associated Risks Factors | www.pipelinereview.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   The FDA advisory committee unanimously rejected rimonabant because of concerns of an increase in suicidal ideation seen in patients taking the highest dose of the medication (20 mg). This drug has been proven in several large studies to not only induce greater weight loss than other strategies,...
July 6, 2007
Whats new in hypertension therapy - nothing , sort of
Analysis of: Exforge Helps Vast Majority of Patients Effectively Control Their Blood Pressure After Failing on Other Medicines, According to New Clinical Data | pharmalive.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Valsartan (an ARB) and amlodipine (a calcium channel blocker) are both useful drugs in treating hypertension and heart failure.  Most patients require more than 1 medication to reach goal in controlling their blood pressure.  Exforge (a combination of valsartan/amlodipine) will...
June 28, 2007
Angiogenesis (Growth factors) for peripheral arterial disease
Analysis of: Vical Licensee AnGes MG Announces Positive Results of Phase 3 Angiogenesis Trial in Japan | www.pipelinereview.com
Author: Forrest Rubenstein, Cardiac, Thoracic and Vascular Surgeon, Rubenstein Cardiovascular and Thoracic Surgery
   Peripheral arterial disease is a major problem in this country which is only recently being recognized for the epidemic that it has become.  This problem (PAD) coexists with coronary disease (heart attacks) and cerebrovascular disease (strokes) and has been neglected and underdiagnosed...

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