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March 23, 2007The Black box warning of the Calcineurin inhibitors is faulty
Analysis of: Black Box Warning for Topical Calcineurin Inhibitors and the Death of Common Sense | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
I totally agree with this article. The conclusions from the FDA are incorrect, and the data appear to indicate that the TCI's are actually protective!!!! In any event it has created a false sense of a problem, where none exists, and decreases the use of these agents, which are safer than the existing...
March 23, 2007Acne scarring an under treated condition
Analysis of: Treatment of Acne Scarring | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article is a good summary of the currently available techniques of excision, subcision, and resurfacing. It does not mention dermal grafting, a technique that I personally use quite often. The maximum correction that one can achieve is 50-70% with a combination of multiple techniques.
March 21, 2007Is anyone talking about the downtime?
Analysis of: Blast Away Wrinkles | www.ivanhoe.com
Author: Gregory Buford, Plastic Surgeon and Medical Director , BEAUTY by BUFORD
Noninvasive modalities are becoming increasingly popularPlasma therapy represents a spin on an old way of rejuvenating skinTo achieve dramatic results, there is a dramatic amount of downtime
March 19, 2007Cytochroma Cta018 cream
Analysis of: Cytochroma Completes Enrollment In Phase II Psoriasis Trial | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This product by Cytochroma is a vitamin D analog which is similar to Dovonex, a product that has been used for 13 years. Its efficacy is modest at best. This product may, repeat may be better, because it activates the vitamin D pathway, and inhibits catabolism of Vitamin D. Whether this makes the product...
March 19, 2007Portrait Plasma technology by Rhytec
Analysis of: Blast Away Wrinkles | www.ivanhoe.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This technology is new, but no better than other resurfacing technologies like Sciton and Fraxel. Pain is significant, healing takes weeks, and there are risks as in other resurfacing technologies. The final results are good. A head to head comparison with other technologies is needed.
March 19, 2007
Plasma is Hot
Analysis of: Blast Away Wrinkles | www.ivanhoe.com
Author: GLG Expert Contributor
Analysis of: Blast Away Wrinkles | www.ivanhoe.com
Author: GLG Expert Contributor
Balanced article shows that there are limitations, but essentially it is good technology that reminds us that we need downtime to get significant effects. The promise of no down time lasers has been shown to not be clinically effective. Exiting new technology showcased.
March 12, 2007Excessive antibiotic use leads to resistance
Analysis of: Proof Nailed Down that Antibiotics Use Leads to Resistance | www.medpagetoday.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article has validity in dermatology due to the increased resistance seen in acne. This may have clinical significance in that we may be seeing resistance to therapy in acne patients after prolonged use.Collagenex corp. is developing non antibiotic medications for acne and rosacea that are...
March 12, 2007
Makes it bigger
Analysis of: Nonsurgical wrinkle filler wins by a nose | www.shreveporttimes.com
Author: GLG Expert Contributor
Analysis of: Nonsurgical wrinkle filler wins by a nose | www.shreveporttimes.com
Author: GLG Expert Contributor
The hump may have the appearance of having gone but in reality the nose is now larger as the lower areas have been raised. Removing the material is difficult so make sure the patient understands what the downside is.
March 12, 2007
Not exactly what they claim
Analysis of: New Survey Reveals Dramatic Rise in Non-Invasive Procedures in Facial Plastic Surgery | www.surgicenteronline.com
Author: GLG Expert Contributor
Analysis of: New Survey Reveals Dramatic Rise in Non-Invasive Procedures in Facial Plastic Surgery | www.surgicenteronline.com
Author: GLG Expert Contributor
Although the desires and performance of less invasive or noninvasive procedures has gone up, the stats can be confusing. Firstly the non or less invasive procedures do not hold up as long and do not give as much of an improvement, patients need to be told it will be a subtle change, and they need to...
March 8, 2007Relieva results are encouraging
Analysis of: Allegiance Equity Corporation Announces Positive Results of In Vitro Studies and an Open Label Trial for Relieva(R) in Treating Atopic Dermatitis | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
The open label trial results for the product Relieva from Allegiance Equity Corp. are encouraging. However the trials need to be double blinded, and with a much larger number of patients. If the product can be compared to a low- mid potency topical steroid in efficacy, then it will be successful. Homeopathic...
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Source Article | Expert Analyses
Use of Antipsychotics in Children Is Criticized
www.nytimes.com
Scientists recommend 'black box' for Avastin
www.fiercepharma.com
Are Costly Diabetes Pills Doing Any Good?
www.pharmalot.com
How a Drug Maker Tries to Outwit Generics
online.wsj.com
Use of Antipsychotics in Children Poses Risks of Adverse Effects
November 26, 2008
Avastin and clots? News to me. Black box warning? Why?
November 24, 2008
Off Label Use Can Be Prevented
November 24, 2008
Gardasil will most certainly be approved for boys
November 24, 2008
Medivations's (MDVN) Dimebon - We've Seen This Movie Before
November 24, 2008

