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GLG News by Addiction Medicine Psychiatrists (US)

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March 28, 2007
Why would kick-boxing NOT cause brain damage?
Analysis of: Kickboxing 'causes brain damage' | news.bbc.co.uk
Author: GLG Expert Contributor
I would expect that the the neuroendocrine effects of kick-boxing would be but one of the effects of repeated head trauma in kick-boxing.  The advantage of this observation is that blood levels of hormones can be measured reliably. 
March 28, 2007
Duloxetine use should not change much because FDA approval for a new indication rarely means very much
Analysis of: FDA Approves Duloxetine for Anxiety | journals.elsevierhealth.com
Author: GLG Expert Contributor
Duloxetine is most widely used for chronic pain as a "depressive equivalent."  Eli Lilly is attempting to expand this market by obtaining FDA approval for anxiety.  Most psychiatrists do not really pay attention to these belated indications as they have already been using duloxetine and their...
March 21, 2007
Blackouts and disinhibition are not only due to alcohol
Analysis of: FDA Issues Warning on Sleeping Pills | www.nytimes.com
Author: GLG Expert Contributor
FDA warnings were issued describing episodic disinhibition and poor recollection as a result of the short acting sleeping pills--the ones that fly over your bed as does a butterfly to cause you to sleep gently through the night and awake the next morning fresh and rested.  If you combine these...
March 20, 2007
If you had cancer would you expect to be treated? Why not for methamphetamine addiction?
Analysis of: Arizona Governor Announces $2.5 Mill. For Meth Abuse Treatment | www.allamericanpatriots.com
Author: GLG Expert Contributor
Ms. Napolitano of Arizona shows wisdom in giving state funds to help implement treatment for methamphetamine addiction.  The analogy to treatment of cancer is not farfetched--addiction deserves the same public outcry as has done so much for cancer research and treatment.  This writer has coined...
March 20, 2007
Thiamine deficiency will make you forget you had weight-loss surgery
Analysis of: Vitamin B1 lack after weight-loss surgery can cause neurological problems | www.cbc.ca
Author: GLG Expert Contributor
The Wernicke-Korsakoff syndrome is a well described neuropsychiatric syndrome which results from thiamine (vitamin B1) deficiency characterized by an acute phase (confusion, unsteady gait, and paralysis of eye movements).  In clinical medicine, it is typically associated with alcohol dependence,...
March 19, 2007
Lower prices may lead to greater misuse
Analysis of: Ranbaxy Receives Tentative FDA Approval to Manufacture and Market Zolpidem Tablets | pharmalive.com
Author: GLG Expert Contributor
Treatment of insomnia with medications has led since the 1880's to increased use, and eventually problem use and dependence. Most thoughtful physicians will agree that treatment of insomnia with "sleeping pills" is not often effective for the long-term.
March 19, 2007
Use opioid painkillers chronically and you will get addicted--no ands or buts
Analysis of: Experts Seek Options on Painkiller Abuse | www.topix.net
Author: GLG Expert Contributor
The notion that pain can be relieved with opioids indefinitely is not based in reality. Opioid pain medications that are currently available are mostly not effective chronically, yet the pharmaceutical industry is knocking itself out to make formulations that will achieve this goal. Yet, mostly they...
March 15, 2007
Do a formal clinical trial once you know it works
Analysis of: Depomed Completes Patient Enrollment in Phase 3 Clinical Trial of Gabapentin GR in Postherpetic Neuralgia | www.redorbit.com
Author: GLG Expert Contributor
Gabapentin has been used for at least a decade for neuropathic pain and most of us are quite convinced it works well.  It is about time that we will have a formal clinical trial to prove that we have been doing the right thing all along.
February 26, 2007
This is your brain on drugs
Analysis of: Cocaine Changes Proteins And Brain Function | www.medicalnewstoday.com
Author: GLG Expert Contributor
The investigators in this study used relatively new molecular techniques to identify approximately 50 proteins that are differentially expressed in individuals who died from cocaine, compared to those that did not.
February 26, 2007
Genes are only part of the story
Analysis of: Personalized Medicine Promises Tailor-Made Diagnoses, Treatments | news.nationalgeographic.com
Author: GLG Expert Contributor
Personalized medicine has tremendous cache. Everyone wants what is best for them when they are sick and this notion feeds into this human fear and insecurity. But there is more to people than genes alone.

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