FDA Approves EVOLENCE®, a New Generation Collagen-Based Facial Filler

Evolence is an injectable filler material that is made by an "advanced collagen GLYMATRIX™ Technology."  Collagen has generally fallen out of favor amongst aesthetic physicians due to its short duration of action.  Evolence will have to demonstrate that it is superior to the plethora of other injectable filler materials currently available to gain market share.  To do so will...

Over the past few years, noninvasive cosmetic procedures have skyrocketed.  Soft tissue injectable fillers are among those procedures that are rapidly growing.  Up until now, hyaluronic acid (HA) fillers have been the mainstay.  With the emergence of Envolence, we have a new twist on an old product--collagen.  Since this does not involve skin testing and can be used at the same...

makes no sense to introduce a product that does not last as long as others on the market unless you are going t sell it to the patient at a substantial prce savings. Even in that scenario, needle fatigue wil eventually make the patient seek a different filler.

Evolence comes from pigs and religious concerns are important about to be injected. Its softness is now outdated.

This article is important because it outlines the rationale and benefits of the new collagen based filler from Ortho-Neutrogena/ Johnson and Johnson. This filler appears to last at least 6 months, and does not require pre testing as other collagen based fillers have needed in the past. The fact that this filler has been used overseas is reassuring. The remaining products will have some increased competition,...

Here are the concerns.1. The collagen injections by Collagen Corp could not compete with hyaluronic acid because it typically does not last longer.  Typically, collagen does not last as long in certain facial regions.2.  There are structural changes that would have to be done on collagen to make it resistant to collagenase so that it will be stable.  How much cross linking is there....