Published at: www.thelancet.com
Novo Nordisk's Liraglutide Wins in Obesity Too
October 29, 2009
Results from a 20-week study of the GLP-1 analog liraglutide in obese and overweight patients were recently published in The Lancet. In the trial, 564 patients were randomized to one of six groups: orlistat (120 mg, 3 times daily), placebo, and liraglutide 1.2 mg, 1.8 mg, 2.4 mg, or 3.0 mg. The trial involved a three-week screening period,a two-week run-in period, a 20-week double blind study period, and a 84-week open label follow up.