Xolair apprehension

Implications: There is a concern about anaphylaxis secondary to Xolair administration and this may result in longer waiting times after the administration of the drug.

Analysis: If there is a black box warning placed on Xolair, this would imply a 2 hour waiting time after drug administration. This would result in a significant fall off of patients receiving the drug secondary to this waiting period. I am not sure if the black box warning will actually take place as of yet and Genentech is planning a rebuttal to present to the FDA according to the recent meeting at the AAAAI in San Diego.