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November 26, 2007

NF KappaB decoy technology innovative in inflammatory skin diseases

This analysis is solely the work of the author. It has not been edited or endorsed by GLG.
Analysis By:
Sunil Dhawan, MD, Clinical Assistant Professor of DermatologySunil Dhawan, MD
Clinical Assistant Professor of Dermatology, Stanford University
Implications: Meyer Pharmaceutical acquisition of a NF-kB decoy is interesting in that this would be the first new technology in this area since the topical immunomodulators like Protopic/ Elidel were released. The preliminary work looks good, and phase 2 trials in both atopic dermatitis and psoriasis would be necessary to render a complete opinion. Corgentech Inc. had a similar technology, but no recent work has been done by them .

Analysis:   This will have a significant impact on all companies that make products for atopic dermatitis and psoriasis like Galderma, Skin Medica, Stiefel, Medicis, etc. The effect would be profound if the phase 2 results show significantly positive results.

Other Analyses of the Same Source Article:
Decoys and red-herrings
November 26, 2007, Author: GLG Expert Contributor
NF-kB decoy, licensed for more clinical trial by Dr Xin Mao
November 23, 2007, Author: GLG Expert Contributor

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