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February 14, 2007

ISTA takes the lead in topical NSAID therapy

Analysis of: ISTA Pharmaceuticals Announces Positive Preliminary Xibrom Once-daily Formulation Clinical Results From U.S. Phase III Trials | pharmalive.com
This analysis is solely the work of the author. It has not been edited or endorsed by GLG.
Analysis By:
Barry Schechter, MD, Director of Corneal and External DiseasesBarry Schechter, MD
Director of Corneal and External Diseases, Florida Eye Microsurgical Institute, Inc.
Implications: There has been a sea change in the treatment of postoperative cataract patients. The addition of a nonsteroidal has significantly reduced postoperative complications such as edema, discomfort and inflammation.

Compliance with all medications is always an issue, and the use of a once daily medication potentially makes this a non-issue. I have been impressed with the BID Xibrom and my patients in the phase 3 trial did exceptionally well.

I expect that this will be well received, pending acceptance of formularies.

Analysis: I believe that this will be available by Q4 2007.

Xibrom BID has a 7% market share and exponential growth; the improvements here should help continue to grow market share.

Other Analyses of the Same Source Article:
Xibrom: A potential blockbuster for post-operative eye pain?
March 7, 2007, Author: Sanjay Rao, MD, Medical Director, Lakeside Eye Clinic

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