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April 4, 2008

Genetic drivers of lung cancer risk identified.

Analysis of: Studies Find Genetic Link to Smoking | www.nytimes.com
This analysis is solely the work of the author. It has not been edited or endorsed by GLG.
Analysis By:
Kenneth Algazy, MD, Clinical Professor of Medicine , University of Pennsylvania School of Medicine - CCKenneth Algazy, MD 
Clinical Professor of Medicine , University of Pennsylvania School of Medicine - CC
Implications: Gene driven nicotine receptors will predispose to increased smoking. What will this lead to?? Increased addiction due to mutations increases cancer risk.

Analysis: If smokers are found to harbor this mutation perhaps altering the sites can decrease smoking and thus decrease the risk?

Again this is a reflection of the value of gene mutation detection, and as the tests in this and other malignancies become available they will have a commercial impact.


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