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March 19, 2007

Cytochroma Cta018 cream

Analysis of: Cytochroma Completes Enrollment In Phase II Psoriasis Trial | www.pipelinereview.com
This analysis is solely the work of the author. It has not been edited or endorsed by GLG.
Analysis By:
Sunil Dhawan, MD, Clinical Assistant Professor of DermatologySunil Dhawan, MD
Clinical Assistant Professor of Dermatology, Stanford University
Implications: This product by Cytochroma is a vitamin D analog which is similar to Dovonex, a product that has been used for 13 years. Its efficacy is modest at best. This product may, repeat may be better, because it activates the vitamin D pathway, and inhibits catabolism of Vitamin D. Whether this makes the product more effective is unclear. The results of the trial are critical.

Analysis: I think that it will be as good / slightly better than Dovonex, the current Vitamin D analog. This product has modest benefit in psoriasis. It is best used with a topical steroid.


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