August 18, 2008
Stents vs. Drugs: Same for Patients, Very Different for Providers
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Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.comAuthor: GLG Expert ContributorTo stent or not to stent: presence and degree of coronary artery disease, effectiveness of medical therapy and significance of symptoms and, therefore, indications for coronary stents placement are determined by very same physicians who place stents. Stents are reimbursed 10-20 times better than medical management.
August 18, 2008
Electronic Medical Records-EMR
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Majority of Patients Want Doc to use EHRs: Study | www.modernhealthcare.comAuthor: GLG Expert ContributorElectronic Medical Records (EMR) or Electronic Health Records (EHR) are the most modern formats emerging in the medical field thanks to the innovations emerging in Information Technology Segment. Most of the current day patients are aware of medical attention needs unlike the olden past. However, the nuances of EMR are yet to be propagated by the medical fraternity or by the providers as such...
August 18, 2008
Agreement with Abbott will help Crestor sales
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Abbott signs deal to promote Crestor in U.S. | www.chicagotribune.comAuthor: GLG Expert ContributorThe co-marketing with Abbott will undoubtedly help Crestor sales, if they can effectively develop a fenofibrate-rosuvastatin combination, and avoid over-burdening physicians with reps. However, there are other factors that will probably have a larger impact.
August 18, 2008
30:70 chance of approval
Analysis of:
AstraZeneca and Bristol-Myers Squibb Submit New Drug Application in the United States and Marketing Authorisation Application in Europe for ONGLYZA™ (Saxagliptin) for the Treatment of Type 2 Diabetes | www.astrazeneca.comAuthor: GLG Expert ContributorGiven what happened to Galvus, and the similar poor selectivity of saxagliptin for DPP-4 over other isoforms, I think that FDA approval is unlikely. There was also some data on changes in white count presented at the ADA that will hurt this agent. The FDA move to recommend outcome studies for DM treatments may also hurt them.
August 18, 2008
Promising start but more data needed
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Lilly Diabetes Drug Shows a Life-Extending Promise | www.nytimes.comAuthor: GLG Expert ContributorThis will probably help Byetta sales modestly. However, the numbers ere small, it was a non-randomized comparison, and may be that Byetta use was a surrogate for less sulfonurea use, lower doses of insulin or no insulin at all (any of which may be harmful). However, the main barrier to more widespread Byetta use is the need for BID injections and the training required. These data may provide more...
August 15, 2008
Less and less evidence to favor coronary stenting
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Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.comAuthor: GLG Expert ContributorThis study pretty convincingly shows that there is only a short term symptom and quality of life improvement associated with coronary stenting, as compared to good quality pharmacological treatment. This will decrease the pressure for aggressive revascularization of any and all coronary lesions (which has been pushed by many interventionalists). If the results are accepted by the health...
August 15, 2008BiovaxID: Does It Work?
Analysis of:
Biovest Reports Results for Patients Treated with Anti-Cancer Vaccine: BiovaxID(R) Demonstrates Clinically and Statistically Significant Improvement of Disease-Free Survival in Non-Hodgkin's Lymphoma in Pivotal Phase 3 Clinical Trial | biz.yahoo.com
Author: Donald Tsai,
Assistant Professor of Medicine, University of Pennsylvania Cancer Center 1) BiovaxID shows a 100% improvement in DFS at 3 years (p=0.24) 2) BiovaxID shows an improvement in median overall DFS with a significant P value (p=0.047) 2) This is the first lymphoma vaccine with a suggestion of activity. 3) BiovaxID shows evidence of activity despite the failure of 2 other lymphoma vaccines made by Genitiope and Favrille.
August 15, 2008
Byetta - what needs to be done
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Lilly Diabetes Drug Shows a Life-Extending Promise | www.nytimes.comAuthor: GLG Expert ContributorVery interesting results; Need more information. Did Janumet also result in weight loss? does weight loss disappear after a while? Was weight loss associated with an improvement in cardiovascular hemodynamics, lipid profile and elasticity of blood vessels; it will be interesting to see if the secondary features of diabetes mellitus will also be eliminated with Byetta. it will be interesting also to...
August 15, 2008Astra-Zeneca and Abbott partner on promoting Crestor..should Pfizer beware?
Analysis of:
Abbott signs deal to promote Crestor in U.S. | www.chicagotribune.com
Author: Joseph Bertino,
Independent Consultant, Bertino Consulting -Crestor sold 2.8 billion dollars in sales in the recent year, will this partnership result in long term exponential growth? -What are the implications for Crestor with generic simvastatin and with Lipitor going generic in the next few years? -Is a combination product going to bolster Crestor sales?
August 14, 2008
Imaging and therapeutic agents for Brain tumor ( glioblastoma multiforme)
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Recent Popular New Reports About Senator Ted Kennedy's Brain Tumor | www.cnn.comAuthor: GLG Expert Contributor1. Public awareness and budget for research for brain will increase. 2. Federal funding should increase for GBM ( Glioblastoma multiforme) 3. More researchers will join in this field