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GLG News in Healthcare

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Mark PackerAugust 19, 2008
Visian ICL: Premium Channel for the Extremely Nearsighted
Analysis of: Insiders Buy Staar as Lasik Alternate Shows Potential (Update2) | www.bloomberg.com
Author: Mark Packer, Clinical Associate Professor of Ophthalmology, OREGON HEALTH & SCIENCE UNIVERSITY - CC
The Visian ICL (Implantable Collamer Lens) is an exquisitely precise technology for the correction of high degrees of nearsightedness -- much higher than the reach of laser refractive surgery such as LASIK and PRK.  Given the price of the ICL and the intraocular surgey required for its implantation, the out-of-pocket expense for the patient is about US$4000 per eye (about...
August 18, 2008
Courage trial should redefine care in America
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.com
Author: GLG Expert Contributor
Most hospitals are financially built on their heart programs. The "agressive" medical arm is conservative by our standards yet as good as stents at far less cost. If this was truly pursued by large companies with TPA insurance plans, their overall cost would drop with large savings in healthcare costs. They will need to eliminate disincentives (copays) to proper prescribing, replacing them with...
August 18, 2008
Stents vs Coronary Surgery
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.com
Author: GLG Expert Contributor
As a sales executive in the cardiac surgery market for many years, I have been involved with many aspects of this industry as well as having met many cardiac surgeons and seen numerous coronary surgeries. Overall, the success rate with stents is poor vs coronary bypass and certain follow up medications. The ratio of success vs failure is impressive when studying the success of stents.   Edward...
August 18, 2008
Byetta saves lives
Analysis of: Lilly Diabetes Drug Shows a Life-Extending Promise | www.nytimes.com
Author: GLG Expert Contributor
The ACCORD trial results were no suprise to our diabetes practice. We have been heavy users of Byetta since launch in 2005, and have seen the same results in our population of > 2000 diabetics with over 700 on Byetta. Since the Simpson et al study in the Canadian Journal of Medicine (CMAJ 2006;174(2):169-74) showing an increase in mortality with sulfonyurea from 1.3 to 2.1 fold, but a decrease...
August 18, 2008
Transparency Without IT Solutions Lacks Substance
Analysis of: Transparency in Healthcare | www.hospitalimpact.org
Author: GLG Expert Contributor
 Transparency adds value by 1) driving knowledge based decision-making 2) building accountability at each decision point and 3) educating consumers  to options and  risks.  In the face of escalating unsustainable cost and the failure of the hospitals to build the infrastructure to drive efficiency, the government and other vested interests are mandating transparency through public...
August 18, 2008
Not too surprising a result
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.com
Author: GLG Expert Contributor
You can only open up an artery so far. Whether you achieve this with drugs, or a mechanical device doesn't seem to matter as long as the blood gets flowing again.
August 18, 2008
Stents vs. Drugs: Same for Patients, Very Different for Providers
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.com
Author: GLG Expert Contributor
To stent or not to stent: presence and degree of coronary artery disease, effectiveness of medical therapy and significance of symptoms and, therefore, indications for coronary stents placement are determined by very same physicians who place stents. Stents are reimbursed 10-20 times better than medical management.
August 18, 2008
Electronic Medical Records-EMR
Analysis of: Majority of Patients Want Doc to use EHRs: Study | www.modernhealthcare.com
Author: GLG Expert Contributor
Electronic Medical Records (EMR) or Electronic Health Records (EHR) are the most modern formats emerging in the medical field thanks to the innovations emerging in Information Technology Segment.  Most of the current day patients are aware of medical attention needs unlike the olden past. However, the nuances of EMR are yet to be propagated by the medical fraternity or by the providers as such...
August 18, 2008
Agreement with Abbott will help Crestor sales
Analysis of: Abbott signs deal to promote Crestor in U.S. | www.chicagotribune.com
Author: GLG Expert Contributor
The co-marketing with Abbott will undoubtedly help Crestor sales, if they can effectively develop a fenofibrate-rosuvastatin combination, and avoid over-burdening physicians with reps. However, there are other factors that will probably have a larger impact. 
August 18, 2008
30:70 chance of approval
Analysis of: AstraZeneca and Bristol-Myers Squibb Submit New Drug Application in the United States and Marketing Authorisation Application in Europe for ONGLYZA™ (Saxagliptin) for the Treatment of Type 2 Diabetes | www.astrazeneca.com
Author: GLG Expert Contributor
Given what happened to Galvus, and the similar poor selectivity of saxagliptin for DPP-4 over other isoforms, I think that FDA approval is unlikely. There was also some data on changes in white count presented at the ADA that will hurt this agent. The FDA move to recommend outcome studies for DM treatments may also hurt them.
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