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GLG News in Healthcare

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August 28, 2008
Dangers of Methadone Usage
Analysis of: Dr. Mark Yergin testifies to Congress | www.nytimes.com
Author: William Fink, President, Managed Care Pharmacy Consultants, Inc
Doctors must be educated on the correct use of Methadone if unnecessary deaths are to be avoided.
August 28, 2008
NICE States Novel Therapies for Renal Cell Cancer Too Costly
Analysis of: UK Says Kidney Cancer Drugs Are Too Pricey | www.pharmalot.com
Author: Michael Grossbard, Professor of Clinical Medicine, Columbia University College of Physicians and Surgeons
NICE has stated that the cost of several novel agents for the treatment of renal cell cancer including Sutent, Torisel, Avastin, and Nexavar exceeds the benefit when assessed by quality adjusted life years (QALY) gained from the therapies.
August 28, 2008
The trial that is all about hype
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time | www.bloomberg.com
Author: GLG Expert Contributor
The general public hears the bullet that stents are no better than medications, but the reality that this trial (COURAGE trial) had major flaws, the main being that only 10% of the patients screened participated in the trial. 90% were excluded. Thus, the patients enrolled were not necessarily the typical patients. Also, very few of the new, drug-eluting stents were used. That being said, the initial...
August 27, 2008
A rough in the diamond
Analysis of: FDA Alert: Hemorrhagic or Necrotizing Pancreatitis in Patients Taking Byetta | www.fda.gov
Author: GLG Expert Contributor
If truly an association, this will alter the use of this drug.
August 27, 2008
False economy by companies
Analysis of: Healthways' Guidance Not So Healthy | www.forbes.com
Author: GLG Expert Contributor
Healthways is currently struggling, but hopfully this will only be a temporary local difficulty. In the long run Healthways provides a good service
August 26, 2008
Temozolomide and Thalidomide combination therapy for Malignant Melanoma
Analysis of: Temozolomide And Thalidomide Combination Effective Against Malignant Melanoma Spread To CNS And White Blood Cell Count May Be Prognostic | www.medicalnewstoday.com
Author: GLG Expert Contributor
1.  The phase II clinical trial  of the combination thherapy of ( temozolomide and Thalidomide for Malignant Melanoma is very encourganing. It may open new avenue to treat   malignant melanoma  affecting Brain. 2. This  article is important for use  of combination therapy for other diseases. 3.  May be  other GBM drugs and Thalidomide could be used for...
August 26, 2008
Right Idea, Not Enough Incentive
Analysis of: Europe adopts new pediatric drug rule | www.nationalreviewofmedicine.com
Author: GLG Expert Contributor
Children have long been therapeutic orphans, often relying on off-label use of new drugs which have only been tested on adults. This legislation seeks to remedy that inequality, by encouraging pharmaceutical companies to do more testing in pediatric populations.
Steve RubinsteinAugust 26, 2008
New non steroidal anti-inflamatory for diabetic retinopathy?
Analysis of: Pfizer Inc. Cancels Phase III of Glaucoma Drug Research in Asia | www.biospace.com
Author: Steve Rubinstein, Optometrist, Sound Shore Vision Care
The new prostaglandin analog is not what i find interesting in this article. A new treatment for Diabetic Retinopathy sounds much more interesting
Frederic GoldsteinAugust 26, 2008
Healthways A Market Downturn and Results
Analysis of: Healthways' Guidance Not So Healthy | www.forbes.com
Author: Frederic Goldstein, President and Chief Operating Officer, U.S. Preventive Medicine, Inc.
Healthways reported lower than expected earnings in its current quarter and analysts are pointing to a tightening in the healthcare markets and the fact that Healthways products are expensive. Does this really make sense?
August 25, 2008
No advancement in treatment
Analysis of: FDA Approves ALOXI(R) (Palonosetron HCl) Capsules For Prevention Of Acute Chemotherapy Induced Nausea And Vomiting | www.medicalnewstoday.com
Author: GLG Expert Contributor
This is the 4th in its class of oral antiemetics to control acute phase CINV.  It is likely to be cost-prohibitive in the company of generical ondansetron.  Palonosetron's control of delayed CINV in the IV formulation makes it the better choice among it's class; therefore, losing this indication in the oral form will make it less attractive to use.
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