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GLG News in Healthcare

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Donald FlemingOctober 9, 2008
Beta trial negative, but is it truely blinded
Analysis of: Genentech Set Back by Cancer-Drug Study | online.wsj.com
Author: Donald Fleming, Division Head of Hematology and Oncology, Davis Health System, Inc.
Beta trial implies that Avastin adds to the effectiveness of the other Genentech drug, Tarceva There is an attempt to change treatment gudelines in second line non small treatment
October 8, 2008
All brawn and not enough brains
Analysis of: Pharma's new favorite outsourcing spot: China | www.fiercepharma.com
Author: GLG Expert Contributor
Yes the trend will continue, but with limitations, for now. China IS most definitely already a source for pharmaceutical manufacturing, but has a long way to go before becoming an independent creator of pharmaceutical intellectual property. Once it can, then outsourcing will really take off.
October 8, 2008
Interesting, but be cautious
Analysis of: Lilly Announces Initiation of Second Global Phase III Trial of Investigational Alzheimer's Disease Compound | newsroom.lilly.com
Author: GLG Expert Contributor
Gamma secretase inhibitors are one of several kinds of drugs being studied for the prevention/amelioration of Alzheimer's.  In concept they make sense.
John AnsellOctober 8, 2008
Pfizer focuses down - but at the same time takes on more risk
Analysis of: Pfizer shifts focus to cancer and biotech drugs | ap.google.com
Author: John Ansell, Director, John Ansell Consultancy
As the biggest pharmaceutical company, Pfizer's R & D needs to be more productive than any other company's if it is to survive and prosper. But Pfizer must have new products that are big if they are to make an impact on its bottom line. The conundrum is that disease is a diffuse market, with few very big pharmaceutical products to treat it, and far more smaller ones. Thus in...
October 8, 2008
Avastin/Tarceva/Roche/OSI/Genentech: So much for "synergy" in lung cancer
Analysis of: Genentech Set Back by Cancer-Drug Study | online.wsj.com
Author: GLG Expert Contributor
The primary goal was improved survival- NOT REACHED!!
October 7, 2008
A Tenuous Connection at Best
Analysis of: Protecting a Home From Silent Threat | www.nytimes.com
Author: GLG Expert Contributor
Yes, there are elevated radon levels in some homes, and, yes, there are patients with lung cancer in some homes, as well. But the connection, while it might be intuitive, remains to be solidified.
Steve RubinsteinOctober 6, 2008
A new lens for computer users?
Analysis of: PixelOptics focuses on new lens | www.roanoke.com
Author: Steve Rubinstein, Optometrist, Sound Shore Vision Care
This eyeglass lens designer, Ron Blum has created a new type of Progressive Addition Lens about 6 years ago. It created a new market in Ultra-Premium lenses. Now he is attempting to create a new lens for computer users. I look forward to its introduction next month, and to the creation of new profit opportunity from selling his new design.
October 6, 2008
It will cost moe tim and Money Dealing with China
Analysis of: Pharma's new favorite outsourcing spot: China | www.fiercepharma.com
Author: GLG Expert Contributor
Rising costs in China makes it less attractive Increased regulatory oversight will increase cost and in the long run improve quality Will all of the problems in China result in better products for both the global market and China  or just for the exports?
October 6, 2008
Risky of Safe: can be both depending on patient selection (just like all other drugs).
Analysis of: COPD Medicines: Risky or Safe? | www.webmd.com
Author: GLG Expert Contributor
Of course anticholinergic drugs leave sympathetic stimulation unbalanced. They, therefore, may act in certain individuals as weak sympathomimetic producing arrhythmias, hypertension, tachycardia, vasoconstriction etc. with know sequences, such as atherosclerosis, cerebrovascular and coronary effects. They should be avoided in individuals with well established risk factors.
October 6, 2008
Killer gas from basement is a cause of lung cancer.
Analysis of: Protecting a Home From Silent Threat | www.nytimes.com
Author: GLG Expert Contributor
How somebody can possibly come up with mentioned estimation: "...20,000 people die from radon-induced lung cancer every year..."? Where is the denominator: how many non-smokers with documented constant radon exposure acquire lung malignancy?
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