Vice Director , HUMANITAS MIRASOLE SPA
Member of the Healthcare Council
Federico Cappuzzo, MD, is Professor and Vice Director of the Department of Medical Oncology at Humanitas Mirasole SPA in Milan, Italy. His main fields of interests include the treatment of lung cancer and colorectal cancer. Dr. Cappuzzo is involved in the development of new drugs such as irreversible tyrosine kinase inhibitors for the treatment of non-small cell lung cancer (NSCLC), leading to over 50 publications in peer reviewed journals. He discovered one of the most relevant mechanisms responsible for sensitivity to erlotinib and gefitinib in NSCLC (EGFR FISH testing), as well as the mechanism responsible for sensitivity to cetuximab in colorectal cancer (EGFR FISH testing). He is involved in several translational research studies looking at the mechanisms of resistance and sensitivity to targeted therapy. He has been involved in numerous clinical trials for newly developed therapeutic agents including Avastin, cetuximab, sorafenib, sunitinib, and zactima. (This is me - Update Profile)
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Should we use cetuximab in all NSCLC patients?
June 2, 2008
Erbitux Slightly Boosts Survival in Cancer Study | online.wsj.com
The FLEX trial, a randomized phase 3 study comparing cisplatin-vinorelbine versus the same regimen plus cetuximab, recently showed that the addition of the monoclonal antibody to chemotherapy significantly prolong survival in chemonaive NSCLC. Several aspects could limit the wide use of cetuximab.
| Study Group Name | No. Members |
|---|---|
| Experts in the Leisure & Lodging Council | 4887 |
| Experts in the Automotive Council | 3422 |
| Oncologists (EU) | 761 |
| Oncologists (Germany, France, Italy) | 343 |
| Council Members who Treat Colon/Colorectal Cancer | 214 |
Federico Cappuzzo has not participated in any GLG Live Meetings.