
Medical Research Director of Cholesterol Center, Jewish Hospital
Member of the Healthcare Council
Charles Glueck, MD, is the Medical Director of Jewish Hospital Cholesterol Center in Cincinnati, Ohio. He has expertise in lipids, lipoproteins, interaction of atherosclerosis and thrombosis, thrombosis, human genetics, epidemiology, obstetrics and gynecology, and hematology. Dr Glueck and colleagues have recent extensive published experience with ocular thrombosis, amaurosis fugax, pregnancy loss, osteonecrosis, Prinzmetal's angina, and ischemic stroke. Dr. Glueck is experienced in epidemiology and biostatistics, and design-completion of controlled clinical trials. Dr. Glueck has authored over 600 scientific papers and was an established investigator for AHA, and has been a long-term NIH grantee. Dr Glueck is on the editorial board of Circulation, and is a senior editor of Metabolism. Dr Glueck actively reviews for 25 journals. Dr. Glueck has also consulted for several major drug companies. (This is me - Update Profile)
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CETP INHIBITORS- A PROBABLE CLASS ACTION EFFECT TO BE PROATHEROGENIC
March 6, 2007
CETP INHIBITORS: A PROBABLE CLASS ACTION EFFECT TO BE PROATHEROGENIC | mediaroom.pfizer.com
By reducing fractional catabolic rate and by producing a large, cholesterol rich HDL molecule which could not easily be cleared by hepatic HDL receptors, our research group in Cincinnati thought from the beginning that the CETP inhibitors AS A CLASS would fail, and might even be proatherogenic. Regrettably, with torcetrapib this sequence of events seemed to occur. Our concern is that this is a class effect and that CETP inhibitors are not a fruitful area for further drug development.
| Study Group Name | No. Members |
|---|---|
| Experts in the Leisure & Lodging Council | 4887 |
| Experts in the Automotive Council | 3422 |
| General Cardiologists (US) | 1327 |
| Heart Failure Specialists (US) | 975 |
| Non-Electrophysiologist Cardiologists (US) | 853 |
March 28, 2008 | Boston
GLGi: Lipid Management