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GLG News by this Author
Analyses are solely the work of the authors and have not been edited or endorsed by GLG.
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Critical thinking and creativity in AD research
November 9, 2009
New Treatment Halts Progress of Alzheimer's Disease | www.abdn.ac.uk
The recetn clinical results suggest that plaque removal is not enough to halt progressive neurodegeneration in Alzheimer Disease and prompt some intriguing challenges to the amyloid hypothesis.
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We need to learn more about ProSavin Phase I/II Trial in Parkinson’s disease
October 20, 2009
Oxford BioMedica Announces Update on ProSavin® Phase I/II Trial in Parkinsons Disease And Publication of Preclinical Results | www.pipelinereview.com
This is very interesting news. However, in my judgment it is too early to make a final conclusion concerning this clinical trial. Because it should be taken into account that the growing body of evidence clearly indicates that oxidative stress induced mitochondrial failure appeared to be one of the main reasons for the selective neuronal damages that occurs in Parkinson’s disease.
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Amyloid Beta does not correlate to Alzheimer Disease.
October 12, 2009
Bayer Schering ties-up with AC Immune for trial in Alzheimer´s disease | www.pharmabiz.com
The finding of amyloid-beta (Aβ) deposition in AD brains after death led to the so-called “amyloid hypothesis”. We have extensively reviewed the literature which claims that AD is caused by the deposition of Aβ within structures called senile plaques that invade AD brains and that such plaque formation then leads to further abnormalities within the nerve cells, eventually killing them.
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