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GLG News by this Author
Analyses are solely the work of the authors and have not been edited or endorsed by GLG.
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Treament interruptions in HIV therapy
August 25, 2006
Structured Treatment Interruptions Are Inferior for All Patients in Subanalyses of the SMART Study | www.medscape.com
Investigators have attempted to show that STI (Strategic Treatment Interruptions) will be safe and effective during the course of therapy of HIV infection. Unfortunately, that has been shown several times now, not to be the case.
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Treatment of HIV infected patients
August 24, 2006
Similar Efficacy for 3- and 4-Drug Anti-HIV Regimens | www.medscape.com
Deleting one drug makes for better compliance in patients who have to take many medications daily. It is good to know that the 4th drug does not add much.
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MK-0518 and expanded access approval
August 24, 2006
MK-0518, a Novel Integrase Inhibitor, Is Effective and Well-Tolerated | www.medscape.com
New drug in a class of drug that appears to be safe and effective. A major advance.
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Daptomycin - use in bacteremia
August 24, 2006
Daptomycin versus standard therapy for bacteremia and endocarditis caused by staphylococcus aureus | www.nejm.org
This paper provides the supporting evidence for FDA approval of daptomycin for treating bacteremia and endocarditis. It is not particularly surprising in the results reported within.
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August 23, 2006
Orchid gets FDA okay for Cefotaxime injections | www.newkerala.com
Cefotaxime was a useful third generation cephalosporin but given its need for administration 2-3 times daily (or more) it has been supplanted by other drugs such as ceftriaxone - which is given once daily for most indications
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