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GLG News by this Author

Peplin could be beneficial.

July 26, 2009

Analysis of:Peplin Initiates its Final Phase 3 Clinical Trial for PEP005 Gel in AK | www.pipelinereview.com

New product that only requires 2 application days over an area.  May be useful.  Typical source for a product like this, coming from a plant extract.  Considering that 5-flourouracil has several variations, but all have predictable reactions that need minimally a few weeks to heal, it is worth looking at.  I think that it is a small error in not mentioning the healing process from the therapy.

Antioxidant effect

March 11, 2009

Analysis of:Multivitamins: Fact or Fiction | www.usatoday.com

As I ask patients, what is the antioxidant measure we have for the body to show antioxidants work?

there are some, but basics in dermatology are why we are good at the cosmetics

August 4, 2008

Analysis of:As Doctors Cater to Looks, Skin Patients Wait | www.nytimes.com

1. Dermatologists need to keep the basics in dermatology2. The net return on cosmetics is much better than the net return3. It is important to create a balance that gives an opportunity for dermatology patients while treating cosmetics.4.It may be that many dermatologists are still new in cosmetics.5. It is helpful to have the patients understand the the cosmetics is a progressive expertise from the dermatology.6. Patients become both cosmetic and dermatology patients in our office.

Doctors are in the middle of a large financial battle.

July 21, 2008

Analysis of:Pricey Drugs Put Squeeze on Doctors | online.wsj.com

Unfortunately, the physicians have to buy the drugs and it pits the docs in the middle of the money war of pharmaceuticals.     The battle in between is getting too rough and expensive.          

Concerns about Evolence being successful.

July 2, 2008

Analysis of:FDA Approves EVOLENCE®, a New Generation Collagen-Based Facial Filler | www.investor.jnj.com

Here are the concerns.1. The collagen injections by Collagen Corp could not compete with hyaluronic acid because it typically does not last longer.  Typically, collagen does not last as long in certain facial regions.2.  There are structural changes that would have to be done on collagen to make it resistant to collagenase so that it will be stable.  How much cross linking is there.  Are there polymers inserted.3. Procine collagen still has sequence changes that may still require some allergy testing.  Data needs to be reviewed.4. Measuring Botox, the majority of early users who ended up using the most was dermatologists.  Why did they use a general surgeon for testing.  I would hope that plastic surgeons and dermatologists are really on board for the product to work.  That is the mistake another product line did.

DIfficult market to jump into.

June 18, 2008

Analysis of:GNC, Vitabiotics to tap domestic nutraceutical mart | business-standard.com

The article is interesting.  Unless it is marketed very heavily as a US identified product, I don't think it will work.  The MLM marketing system works very well for them because of the lack of retail presence and retail sales.  That is why the other companies sell well in other Asian countries.  I would recommend that there is some MLM launch with both the systems to get better coverage of product marketing.

As an experienced injector (have injected all fillers including silicone), I have evaluated all the injection materials used and there are concerns with non-medical grade filler materials.

May 23, 2008

Analysis of:Renal Failure Linked to Cosmetic Soft-Tissue Filler Injections | www.medscape.com

This article can be important because problems like this will require proper training and specialties that prove adequate experience.  Additionally, there may need to be more evaluations on the materials used for injection cosmetically.  The experience I have had with injections that are silicone have been very positive.  There appears to be other agents that were added to the silicone.  There is a lack of medical grade material used.  Liquid silicone is medical grade for ophthalmic problems.  There have been mixed silicone injections for many years and that has been a big problem years ago.  With the advent of new FDA approved device materials, I would have assumed that there are fewer problem cases.   I do question the patients or clients who would go to an unlicensed person for injections.

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