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Analyses are solely the work of the authors and have not been edited or endorsed by GLG.

Genetic Testing--ready for all of medicine or just a niche service?

January 12, 2009

Analysis of:Response Genetics, Inc. Signs Amendment to Its Master Service Agreement With GlaxoSmithKline (GSK) as Preferred Provider of Genetic Testing Services | www.devicespace.com

1. Article reports on the developing role of genetic testing in medicine 2. Also highlighted is the growing partnership of genetic testing firms with pharmaceutical industry 3. An area of interest is pharmacogenetics. There is individual response (or lack of response) to many drugs; this has implications for prescribing medication and for developing new drugs that take individual response into consideration

MK-0524 a Welcome Addition to Lipid-Lowering Options

November 27, 2006

Analysis of:Merck's Investigational MK-0524 Significantly Reduced Flushing Caused By Extended-Release Niacin in Phase II Study | biz.yahoo.com

This article is important as it highlights the many benefits of the Niacin drugs. It describes how MK-0524 may significantly increase adherence as it reduces the side effect of flushing.

This article describes preliminary trials with the new formulation clearly showing a reduction in the side effect of flushing.

The article also reiterates the many benefits of Niacin drugs on all parts of the lipid profile: lowering LDL, raising HDL, and lowering Triglyceride.

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